幻听的神经生理学方面。对幻听患者和正常对照者进行的99mTc-（HMPAO）-单光子发射计算机断层扫描研究——初步报告。

Neurophysiological aspects of auditory hallucinations. 99mTc-(HMPAO)-SPECT investigations in patients with auditory hallucinations and normal controls--a preliminary report.

作者信息

Musalek M, Podreka I, Suess E, Nutzinger D, Passweg V, Strobl R, Walter H, Baumgartner C, Lesch O M

机构信息

Department of Psychiatry, University of Vienna, Austria.

出版信息

Psychopathology. 1988;21(6):275-80. doi: 10.1159/000284570.

DOI:10.1159/000284570

PMID:3266341

Abstract

In a symptom-oriented study 17 patients suffering from chronic auditory hallucinations were investigated by means of 99mTc-HMPAO-SPECT and compared with healthy controls. The results confirm the relative frontal hypoactivity in junction with a relative hyperactivity in the basal ganglia and mesial limbic structures in both hemispheres found in a previous pilot study in auditorily hallucinating patients. Our results should fortify the symptom-oriented approach in psychiatric research.

摘要

在一项以症状为导向的研究中，对17名患有慢性幻听的患者进行了99mTc-HMPAO单光子发射计算机断层扫描（SPECT）检查，并与健康对照者进行比较。结果证实了在先前一项针对幻听患者的初步研究中发现的双侧大脑相对额叶低活性，同时伴有基底神经节和内侧边缘结构的相对高活性。我们的结果应会加强精神病学研究中以症状为导向的方法。