Department of Nutrition, University of North Carolina Greensboro, Greensboro, NC, USA.
Mothers Milk Bank of North Texas, Fort Worth, TX, USA.
J Perinatol. 2020 Nov;40(11):1688-1693. doi: 10.1038/s41372-020-0731-0. Epub 2020 Jul 14.
Energy values for human milk are increasingly available clinically, though there are no standards for deriving these values. We compared published calorie methods using a common set of samples.
Ten human milk samples were measured for gross and digestible macronutrients using laboratory methods. Four calorie conversion factors were used: Atwater general (ATW-GEN); Atwater milk specific (ATW-MILK), human milk specific (HUM-MILK), and combustible conversions (COMBUST). Differences in derived calories were assessed using ANOVA.
There was a significant difference (P < 0.001) in calorie values between methods. Gross macronutrients with COMBUST conversion factors produced the highest calorie values (19.4 ± 1.4 kcal/ounce) whereas digestible macronutrients with HUM-MILK conversion factors produced the lowest calorie values (16.3 ± 1.3 kcal/ounce). Mean difference between these values was 3.1 kcal/ounce (95% CI 2.5, 3.7).
Mean calorie difference of 3.1 kcal/ounce is clinically important for preterm infants, suggesting the need for standardization.
人乳的能量值在临床上越来越普及,但目前还没有确定这些值的标准。我们使用一组共同的样本比较了已发表的卡路里方法。
使用实验室方法对 10 个人乳样本进行了宏观和可消化宏量营养素的测量。使用了四种卡路里换算系数:阿特沃特通用系数(ATW-GEN);阿特沃特乳脂专用系数(ATW-MILK)、人乳专用系数(HUM-MILK)和可燃转化系数(COMBUST)。使用方差分析评估衍生卡路里的差异。
方法之间的卡路里值存在显著差异(P<0.001)。使用 COMBUST 转换系数的宏观营养素产生的卡路里值最高(19.4±1.4 千卡/盎司),而使用 HUM-MILK 转换系数的可消化宏量营养素产生的卡路里值最低(16.3±1.3 千卡/盎司)。这些值之间的平均差异为 3.1 千卡/盎司(95%置信区间为 2.5, 3.7)。
3.1 千卡/盎司的平均卡路里差异对早产儿具有临床重要意义,表明需要标准化。