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母乳中能量值的宏量营养素基准推导方法比较。

A comparison of macronutrient-based methods for deriving energy values in human milk.

机构信息

Department of Nutrition, University of North Carolina Greensboro, Greensboro, NC, USA.

Mothers Milk Bank of North Texas, Fort Worth, TX, USA.

出版信息

J Perinatol. 2020 Nov;40(11):1688-1693. doi: 10.1038/s41372-020-0731-0. Epub 2020 Jul 14.

Abstract

OBJECTIVE

Energy values for human milk are increasingly available clinically, though there are no standards for deriving these values. We compared published calorie methods using a common set of samples.

STUDY DESIGN

Ten human milk samples were measured for gross and digestible macronutrients using laboratory methods. Four calorie conversion factors were used: Atwater general (ATW-GEN); Atwater milk specific (ATW-MILK), human milk specific (HUM-MILK), and combustible conversions (COMBUST). Differences in derived calories were assessed using ANOVA.

RESULTS

There was a significant difference (P < 0.001) in calorie values between methods. Gross macronutrients with COMBUST conversion factors produced the highest calorie values (19.4 ± 1.4 kcal/ounce) whereas digestible macronutrients with HUM-MILK conversion factors produced the lowest calorie values (16.3 ± 1.3 kcal/ounce). Mean difference between these values was 3.1 kcal/ounce (95% CI 2.5, 3.7).

CONCLUSION

Mean calorie difference of 3.1 kcal/ounce is clinically important for preterm infants, suggesting the need for standardization.

摘要

目的

人乳的能量值在临床上越来越普及,但目前还没有确定这些值的标准。我们使用一组共同的样本比较了已发表的卡路里方法。

研究设计

使用实验室方法对 10 个人乳样本进行了宏观和可消化宏量营养素的测量。使用了四种卡路里换算系数:阿特沃特通用系数(ATW-GEN);阿特沃特乳脂专用系数(ATW-MILK)、人乳专用系数(HUM-MILK)和可燃转化系数(COMBUST)。使用方差分析评估衍生卡路里的差异。

结果

方法之间的卡路里值存在显著差异(P<0.001)。使用 COMBUST 转换系数的宏观营养素产生的卡路里值最高(19.4±1.4 千卡/盎司),而使用 HUM-MILK 转换系数的可消化宏量营养素产生的卡路里值最低(16.3±1.3 千卡/盎司)。这些值之间的平均差异为 3.1 千卡/盎司(95%置信区间为 2.5, 3.7)。

结论

3.1 千卡/盎司的平均卡路里差异对早产儿具有临床重要意义,表明需要标准化。

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