Anandh Urmila, Kumar Rakesh, Rao Vishnu
Dept of Nephrology, Yashoda Hospitals, Alexander Road, Secunderabad 500003, India.
Dept of Infectious Diseases, Apollo Hospitals, Jubilee Hills, Hyderabad 500033, India.
Case Rep Infect Dis. 2020 Jun 30;2020:8695204. doi: 10.1155/2020/8695204. eCollection 2020.
Calcific uremic arteriolopathy is a rare condition affecting chronic kidney disease (CKD) patients on long-term dialysis. The clinical manifestations include subcutaneous skin necrosis and ulcers secondary to calcification of the subcutaneous blood vessels. The necrotic tissue often becomes a nidus of infection. The prognosis is often poor. We present a case of a renal allograft recipient who developed a subcutaneous necrotic lesion which was subsequently infected by spp. The patient underwent surgical debridement and antifungal therapy. The infection resolved completely. Our case represents agrave underlying condition predisposing a rare and serious posttransplant infection. The outcome was favourable because of early identification and treatment of the infection.
钙化性尿毒症性小动脉病是一种罕见疾病,影响长期透析的慢性肾脏病(CKD)患者。临床表现包括皮下血管钙化继发的皮下皮肤坏死和溃疡。坏死组织常成为感染病灶。预后通常较差。我们报告一例肾移植受者发生皮下坏死性病变,随后被 spp. 感染的病例。患者接受了手术清创和抗真菌治疗。感染完全消退。我们的病例代表了一种严重的基础疾病,易引发罕见且严重的移植后感染。由于对感染的早期识别和治疗,结果良好。