Shah Syed Sikandar, Abdi Abdikarim, Özcem Barçin, Basgut Bilgen
Department of Clinical Pharmacy, Faculty of Pharmacy, Near East University, Nicosia, North Cyprus, Turkey.
Cardiac Surgeon, Near East University Hospital, Nicosia, North Cyprus, Turkey.
PLoS One. 2020 Jul 15;15(7):e0235495. doi: 10.1371/journal.pone.0235495. eCollection 2020.
Despite the presence of effective strategies and standard guidelines for the prevention of deep vein thrombosis (DVT), a considerable proportion of patients at risk of developing thromboembolism did not receive prophylaxis during hospitalization, while others received it irrationally, thus led to unwanted side effects.
This study aimed to evaluate the current thromboprophylaxis practice and management of hospitalized patients at risk of developing DVT, along with the assessment of health care providers (HCPs) knowledge, and attitudes regarding DVT prevention.
An observational study was conducted in the general wards of two leading tertiary university hospitals in Northern Cyprus in which patients from multiple clinics were enrolled to investigate the rational use of DVT prophylaxis using the Caprini risk assessment tool. Patients were also followed for possible complications two weeks post-hospitalization. A cross-sectional study followed to assess the knowledge and attitude of HCPs regarding DVT risks and prophylaxis.
Of the 180 patients enrolled, 47.7% were identified as irrationally managed, 52.3% were identified as rationally managed, 77.8% of patients were identified as having a high level of risk. Notably, Four of thirteen patients who received more thromboprophylaxis developed minor complications. Additionally, 73.3% of nurses had not received DVT education. Furthermore, more than 50% of physicians and nurses achieved a low knowledge score for DVT risks and prophylaxis.
A high degree of irrationality in the administration of thromboprophylaxis therapy to hospitalized patients was observed. The overall scores for HCPs indicated insufficient knowledge of DVT risk assessments and prophylaxis.
尽管存在预防深静脉血栓形成（DVT）的有效策略和标准指南，但相当一部分有发生血栓栓塞风险的患者在住院期间未接受预防措施，而其他患者接受的预防措施不合理，从而导致了不必要的副作用。
本研究旨在评估目前对有发生DVT风险的住院患者进行血栓预防的实践和管理情况，同时评估医护人员（HCPs）对DVT预防的知识和态度。
在北塞浦路斯两家领先的三级大学医院的普通病房进行了一项观察性研究，纳入了来自多个诊所的患者，使用Caprini风险评估工具调查DVT预防措施的合理使用情况。患者在出院后两周还被随访是否有可能的并发症。随后进行了一项横断面研究，以评估HCPs对DVT风险和预防的知识和态度。
在纳入的180例患者中，47.7%被确定为管理不合理，52.3%被确定为管理合理，77.8%的患者被确定为高风险。值得注意的是，在接受更多血栓预防措施的13例患者中，有4例出现了轻微并发症。此外，73.3%的护士未接受过DVT教育。此外，超过50%的医生和护士在DVT风险和预防方面的知识得分较低。
观察到对住院患者进行血栓预防治疗的管理存在高度不合理性。HCPs的总体得分表明他们对DVT风险评估和预防的知识不足。
