Imao Y, Araki Y, Shimizu K, Ando T, Sakai N, Yamada H
Department of Neurosurgery, Gifu University School of Medicine, Japan.
No To Shinkei. 1988 Dec;40(12):1143-50.
Cerebral blood flow (CBF) was studied tomographically in 40 normal volunteers between 25 and 82 years of age in the resting state by single photon emission computerized tomography (Tomomatic 564) accompanied by inhalation of 133Xenon. In order to investigate the reproducibility, five of these received a second examination within 1 hour of the first (group I). Six others received a second examination 7 to 26 days after the first examination (group II). In addition, 123I-IMP SPECT was performed in five out of 40 subjects to compare the difference between 123I-IMP SPECT and 133Xe SPECT. The Tomomatic 564 (Medimatic Inc. Denmark) gives 5 slices of 2 cm thickness simultaneously and its spatial resolution (full width at half maximum, FWHM) as measured with a 133Xenon line source in water was 1.6 cm in the center of each slice. CBF was calculated according to the early picture method and the sequence of picture method described by Kanno and Lassen. Subjects were positioned in the tomograph so that the five transverse sections were located at 1, 3, 5, 7 and 9 cm above and parallel to the orbito-meatal line (OML). Cerebellar flows were obtained from a slice 1 cm above the OML (slice 1) and mean hemispheric flows were obtained from slices 3 cm (slice 2), 5 cm (slice 3), 7 cm (slice 4) and 9 cm (slice 5) above the OML.(ABSTRACT TRUNCATED AT 250 WORDS)
采用单光子发射计算机断层扫描（Tomomatic 564）并吸入133氙，对40名年龄在25至82岁之间的正常志愿者在静息状态下进行脑血流量（CBF）的断层扫描研究。为了研究可重复性，其中5人在首次检查后1小时内接受了第二次检查（第一组）。另外6人在首次检查后7至26天接受了第二次检查（第二组）。此外，对40名受试者中的5人进行了123I-IMP单光子发射计算机断层扫描，以比较123I-IMP单光子发射计算机断层扫描和133Xe单光子发射计算机断层扫描之间的差异。Tomomatic 564（丹麦Medimatic公司）可同时给出5层2厘米厚的切片，其在水中用133氙线源测量的空间分辨率（半高宽，FWHM）在每层切片中心为1.6厘米。根据Kanno和Lassen描述的早期图像法和图像序列法计算CBF。受试者在断层扫描仪中定位，使五个横断面位于眶耳线（OML）上方1、3、5、7和9厘米处且与眶耳线平行。小脑血流量从OML上方1厘米处的切片（切片1）获得，平均半球血流量从OML上方3厘米（切片2）、5厘米（切片3）、7厘米（切片4）和9厘米（切片5）处的切片获得。（摘要截取自250字）
