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新型冠状病毒肺炎孕妇的阴道分泌物中不存在严重急性呼吸综合征冠状病毒2。

SARS-CoV-2 is not present in the vaginal fluid of pregnant women with COVID-19.

作者信息

Aslan Mehmet Musa, Uslu Yuvacı Hilal, Köse Osman, Toptan Hande, Akdemir Nermin, Köroğlu Mehmet, Cevrioğlu Arif Serhan, Özden Selçuk

机构信息

Obstetrics and Gynecology, Sakarya Training and Research Hospital, Sakarya, Turkey.

Medical Microbiology Department, Sakarya Universty, Sakarya, Turkey.

出版信息

J Matern Fetal Neonatal Med. 2022 Aug;35(15):2876-2878. doi: 10.1080/14767058.2020.1793318. Epub 2020 Jul 16.

DOI:10.1080/14767058.2020.1793318
PMID:32669014
Abstract

BACKGROUND

Data concerning the presence of SARS-CoV-2 in the female genital system is scarce; however, this information is important for understanding whether the virus can transmit sexually or from mother to child. The aim of this study was to investigate whether pregnant women with COVID-19 have virus in their lower genital tract.

METHODS

In this cross-sectional study, we present an analysis of prospectively gathered data collected at a single tertiary university hospital from 19 April to 19 May 2020. We included 13 pregnant women hospitalized with suspected COVID-19. Results of laboratory tests, imaging tests, and nucleic acid tests on vaginal swabs for SARS-CoV-2 were also analyzed for pregnant women with a clinical diagnosis of COVID-19.

RESULTS

Twelve pregnant women with confirmed COVID-19 were included in this study. Mean age was 32 ± 7.9 years. All patients had mild symptoms and were followed in the maternity ward, with none of them needing critical care unit follow-up. All lower genital tract samples were negative for SARS-CoV-2.

CONCLUSION

We demonstrated that SARS-CoV-2 was not present in the vaginal fluid of pregnant women. This finding may indicate that the female genital tract is not a route of SARS-CoV-2 transmission.

摘要

背景

关于严重急性呼吸综合征冠状病毒2(SARS-CoV-2)在女性生殖系统中存在情况的数据很少;然而,这些信息对于了解该病毒是否可通过性传播或母婴传播很重要。本研究的目的是调查感染新型冠状病毒肺炎(COVID-19)的孕妇下生殖道是否存在该病毒。

方法

在这项横断面研究中,我们对2020年4月19日至5月19日在一家三级大学医院前瞻性收集的数据进行了分析。我们纳入了13名因疑似COVID-19住院的孕妇。对临床诊断为COVID-19的孕妇,还分析了其阴道拭子的实验室检查、影像学检查和SARS-CoV-2核酸检测结果。

结果

本研究纳入了12名确诊COVID-19的孕妇。平均年龄为32±7.9岁。所有患者症状较轻,在产科病房接受随访,均无需重症监护病房随访。所有下生殖道样本的SARS-CoV-2检测均为阴性。

结论

我们证明了SARS-CoV-2不存在于孕妇的阴道分泌物中。这一发现可能表明女性生殖道不是SARS-CoV-2的传播途径。

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