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[川崎病——儿童新型冠状病毒肺炎的一种新表现形式]

[Kawasaki disease - a new manifestation of COVID-19 in children].

作者信息

Jiao Fu-Yong

机构信息

Center of Diagnosis and Treatment of Kawasaki Disease in Shaanxi Province/Children's Hospital, Shaanxi Provincial People's Hospital, Xi'an 710068, China.

出版信息

Zhongguo Dang Dai Er Ke Za Zhi. 2020 Jul;22(7):677-678. doi: 10.7499/j.issn.1008-8830.2005117.

Abstract

Since the outbreak of coronavirus disease 2019 (COVID-19) in Europe and America, the incidence of Kawasaki disease has significantly increased, which has aroused concern among pediatricians and parents. COVID-19 can cause inflammation reactions of multiple organs, which is similar to the systemic vasculitis of Kawasaki disease, and even COVID-19 can cause skin rash on the extremities of the limbs, which is also similar to Kawasaki disease. The cause of Kawasaki disease is currently unclear, and it cannot be ruled out that COVID-19 is associated with an increased incidence of Kawasaki disease. Therefore, during the epidemic of COVID-19, if children have symptoms similar to Kawasaki disease, intravenous immunoglobulin is recommended as early as possible to reduce the incidence of coronary artery lesions.

摘要

自2019年冠状病毒病(COVID-19)在欧美爆发以来,川崎病的发病率显著增加,这引起了儿科医生和家长的关注。COVID-19可引起多器官炎症反应,这与川崎病的全身性血管炎相似,甚至COVID-19可导致四肢出现皮疹,这也与川崎病相似。目前川崎病的病因尚不清楚,不能排除COVID-19与川崎病发病率增加有关。因此,在COVID-19流行期间,如果儿童出现类似川崎病的症状,建议尽早使用静脉注射免疫球蛋白,以降低冠状动脉病变的发生率。

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本文引用的文献

1
Hyperinflammatory shock in children during COVID-19 pandemic.新冠疫情期间儿童的高炎症性休克
Lancet. 2020 May 23;395(10237):1607-1608. doi: 10.1016/S0140-6736(20)31094-1. Epub 2020 May 7.
2
Kawasaki Disease: Global Burden and Genetic Background.川崎病:全球负担与遗传背景
Cardiol Res. 2020 Feb;11(1):9-14. doi: 10.14740/cr993. Epub 2020 Jan 26.
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Indian J Pediatr. 2016 Oct;83(10):1195-6. doi: 10.1007/s12098-016-2100-8. Epub 2016 Apr 20.
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