超氧化物歧化酶（过氧化物酶）对白介素-1活性影响的研究。
Studies on the effect of superoxide dismutase (peroxinorm) on interleukin-1 activity.
作者信息
Giełdanowski J, Orłowska B
机构信息
Department of Experimental Therapy, Polish Academy of Sciences, Wrocław.
出版信息
Arch Immunol Ther Exp (Warsz). 1988;36(3):245-8.
The experiments were undertaken to determine the effect of Peroxinorm (superoxide dismutase) on the activity of interleukin-1 in vitro. The results give evidence that the influence of the drug examined on the activity/production of interleukin-1 can take different forms, relative to the concentration applied. At higher dilution (10(-7)) Peroxinorm suppressed the activity of Il-1, whereas at lower dilutions it was devoid of this effect. A conceivable mechanism of its activity in the treatment of the inflammations is also discussed.
进行这些实验是为了确定过氧化物歧化酶对白细胞介素 -1体外活性的影响。结果表明，所检测药物对白介素 -1活性/产生的影响，相对于所应用的浓度而言，可以有不同形式。在较高稀释度（10^(-7)）时，过氧化物歧化酶抑制了白介素 -1的活性，而在较低稀释度时则没有这种作用。文中还讨论了其在治疗炎症中可能的活性机制。
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