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1型糖尿病患者孕期急性夏科氏神经关节病的发病情况。

The onset of acute Charcot neuroarthropathy during pregnancy in patients with type 1 diabetes.

作者信息

Dardari Dured, Penfornis Alfred, Hartemann Agnes

机构信息

Diabetology Department, Centre Hopitalier Sud Francilien, Corbeil-Essonnes, France.

Sorbonne Université, Paris, France.

出版信息

Endocrinol Diabetes Metab Case Rep. 2020 Jul 15;2020. doi: 10.1530/EDM-20-0002.

DOI:10.1530/EDM-20-0002
PMID:32669476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7424321/
Abstract

SUMMARY

We report the onset of acute Charcot neuroarthropathy during pregnancy in two patients with type 1 diabetes using retrospective review of case notes. We describe for the first time the onset of acute Charcot neuroarthropathy during pregnancy in two patients with type 1 diabetes. Pregnancy may promote the onset and worsening of a number of diabetic complications. A link between pregnancy and the onset of acute Charcot neuroarthropathy is demonstrated for the first time in this report.

LEARNING POINTS

Patients with already diagnosed sensitive neuropathy can develop an active phase of Charcot neuroarthropathy during pregnancy. The rapid correction of hyperglycaemia may induce an active phase of Charcot neuroarthropathy during pregnancy.

摘要

摘要

我们通过回顾病例记录报告了2例1型糖尿病患者在孕期发生急性夏科氏关节病。我们首次描述了2例1型糖尿病患者在孕期发生急性夏科氏关节病。妊娠可能促使多种糖尿病并发症的发生和恶化。本报告首次证实了妊娠与急性夏科氏关节病发病之间的联系。

学习要点

已诊断为感觉性神经病变的患者在孕期可能发展为夏科氏关节病的活动期。高血糖的快速纠正可能在孕期诱发夏科氏关节病的活动期。

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本文引用的文献

1
Multifocal (tarsus and knee) activation of neuroarthropathy following rapid glycaemic correction.神经关节病多灶性(跗骨和膝关节)激活,与血糖快速校正相关。
J Diabetes Complications. 2019 Dec;33(12):107438. doi: 10.1016/j.jdiacomp.2019.107438. Epub 2019 Sep 12.
2
The Charcot foot: pathophysiology, diagnosis and classification.夏科氏足:病理生理学、诊断与分类
Bone Joint J. 2016 Sep;98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038.
3
Charcot neuroarthropathy after simultaneous pancreas-kidney transplantation: risk factors, prevalence, and outcome.胰肾联合移植术后的夏科氏神经关节病:危险因素、患病率及预后
Clin Transplant. 2015 Aug;29(8):712-9. doi: 10.1111/ctr.12572. Epub 2015 Jul 14.
4
Diabetic nephropathy but not HbA1c is predictive for frequent complications of Charcot feet - long-term follow-up of 164 consecutive patients with 195 acute Charcot feet.糖尿病肾病而非糖化血红蛋白可预测夏科氏足的频繁并发症——164例连续195只急性夏科氏足患者的长期随访
Exp Clin Endocrinol Diabetes. 2012 Jun;120(6):335-9. doi: 10.1055/s-0031-1299705. Epub 2012 Mar 15.
5
Neuro-osteoarthropathy of the foot-radiologist: friend or foe?足部神经骨关节病——放射科医生:是朋友还是敌人?
Semin Musculoskelet Radiol. 2010 Sep;14(3):365-76. doi: 10.1055/s-0030-1254525. Epub 2010 Jun 10.
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Treatment-induced diabetic neuropathy: a reversible painful autonomic neuropathy.治疗诱导性糖尿病性神经病:一种可逆转的痛性自主神经病。
Ann Neurol. 2010 Apr;67(4):534-41. doi: 10.1002/ana.21952.
7
Impact of pregnancy on the progression of diabetic retinopathy in Type 1 diabetes.妊娠对1型糖尿病患者糖尿病视网膜病变进展的影响。
Diabet Med. 2001 Jul;18(7):573-7. doi: 10.1046/j.1464-5491.2001.00535.x.
8
Diabetic retinopathy in pregnancy.妊娠期糖尿病性视网膜病变
Br J Ophthalmol. 1997 Mar;81(3):249-51. doi: 10.1136/bjo.81.3.249.
9
Neuro-arthropathy (Charcot joints) in diabetes mellitus (clinical study of 101 cases).糖尿病性神经关节病(夏科关节)(101例临床研究)
Medicine (Baltimore). 1972 May;51(3):191-210. doi: 10.1097/00005792-197205000-00006.