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抗阻训练对健康受试者动脉僵硬度的影响:系统评价和荟萃分析。

Effect of Resistance Training on Arterial Stiffness in Healthy Subjects: A Systematic Review and Meta-Analysis.

机构信息

School of Arts, Sciences and Humanities, University of São Paulo, Rua Arlindo Béttio, 1000, Vila Guaraciaba, São Paulo, 03828-000, Brazil.

Department of Physical Education, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil.

出版信息

Curr Hypertens Rep. 2020 Jul 15;22(8):51. doi: 10.1007/s11906-020-01065-x.

Abstract

PURPOSE OF REVIEW

The aim of this systematic review and meta-analysis was to investigate the effect of resistance training on arterial stiffness (AS) in healthy subjects. Two electronic databases (PubMed and Scielo) were searched for randomized controlled trials comparing the effect of dynamic and/or isometric resistance training stand-alone versus non-exercise control group on AS assessed by pulse wave velocity (PWV) in healthy subjects. Random-effects modeling was employed to compare delta changes (post-pre-intervention) in AS between the resistance training and control group. Data were reported as weighted mean difference (MD) and its 95% confidence intervals (CI). Statistical significance was set at 5%.

RECENT FINDINGS

A total of 10 studies involving 310 participants (46.5% female; resistance training groups, n = 194; control groups, n = 116) were included in the meta-analysis. Comparing changes from pre- to post-resistance training groups versus control groups, no differences were observed in PWV (MD - 1.33 cm/s (95% CI - 34.58 to 31.91), p = 0.94, I = 91%). Resistance training stand-alone does not elicit changes (i.e., improvement or impairment) on AS in healthy subjects, but the high heterogeneity suggests influence of training protocol and/or personal characteristics that should be investigated in the future.

摘要

目的

本系统评价和荟萃分析的目的是研究抗阻训练对健康受试者动脉僵硬度(AS)的影响。我们在两个电子数据库(PubMed 和 Scielo)中检索了比较单纯抗阻训练与非运动对照组对健康受试者 AS(通过脉搏波速度(PWV)评估)影响的随机对照试验。采用随机效应模型比较抗阻训练组和对照组在 AS 方面的 delta 变化(干预前后)。数据以加权均数差(MD)及其 95%置信区间(CI)报告。统计学显著性设为 5%。

最新发现

荟萃分析共纳入 10 项研究,涉及 310 名参与者(女性占 46.5%;抗阻训练组 n = 194;对照组 n = 116)。与对照组相比,从抗阻训练前到后,PWV 无差异(MD -1.33cm/s(95%CI -34.58 至 31.91),p = 0.94,I = 91%)。单纯抗阻训练不会引起健康受试者 AS 的变化(即改善或损害),但高度异质性表明训练方案和/或个体特征有影响,未来需要进一步研究。

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