Faculty of Chemistry, University of Science, Ho Chi Minh City, Vietnam.
Vietnam National University, Ho Chi Minh City, Vietnam.
Z Naturforsch C J Biosci. 2020 Jul 16;76(1-2):49-53. doi: 10.1515/znc-2020-0136. Print 2021 Jan 27.
From an EtOAc-soluble fraction of the stem barks of (Anacardiaceae), decumbic anhydride () and four known compounds - were isolated. Their chemical structures were elucidated based on the spectroscopic data interpretation. The GIAO-DFT calculation of C NMR chemical shifts was carried out to clarify the structure of . The absolute configuration of was assigned based on the Cotton effects in its ECD spectrum. Compound showed potent tyrosinase inhibitory activity with an IC value of 52.2 μM.
从腰果（漆树科）茎皮的 EtOAc 可溶部分中，分离得到 decumbic 酐（）和四个已知化合物。根据光谱数据解释阐明了它们的化学结构。通过 GIAO-DFT 计算对 13C NMR 化学位移进行了计算，以阐明其结构。根据其 ECD 光谱中的 Cotton 效应，确定了 的绝对构型。化合物 对酪氨酸酶表现出很强的抑制活性，IC 值为 52.2 μM。
