Faculty of Chemistry, University of Science, Ho Chi Minh City, Vietnam.
Vietnam National University, Ho Chi Minh City, Vietnam.
Nat Prod Res. 2022 Jul;36(14):3737-3740. doi: 10.1080/14786419.2020.1871341. Epub 2021 Jan 18.
From the EtOAc-soluble extract of the stems of , one new lignan, (+)-(8,8')-5'-methoxy-4,4'-di--methylsecoisolariciresinol (), together with five known compounds () were isolated. Their structures were elucidated on the basis of NMR spectroscopic interpretation. The absolute configuration of was determined based on the Cotton effects in the ECD spectrum. In the tyrosinase inhibitory activity test, -hydroxybenzoic acid () showed the strong effect, with an IC value of 9.35 µM.
从 茎的 EtOAc 可溶部分中，分离得到一种新的木脂素，（+）-（8,8'）-5'-甲氧基-4,4'-二--甲基-脱甲氧基异落叶松脂素（），以及五种已知化合物（）。根据 NMR 波谱解析，确定了它们的结构。通过 ECD 光谱中的 Cotton 效应确定了 的绝对构型。在酪氨酸酶抑制活性测试中，-羟基苯甲酸（）表现出较强的抑制效果，IC 值为 9.35 μM。
