Kim C J, Chi J G, Kim Y I
Department of Pathology, College of Medicine, Seoul National University, Korea.
J Korean Med Sci. 1988 Jun;3(2):63-71. doi: 10.3346/jkms.1988.3.2.63.
We reviewed clinical and pathologic characteristics of 18 cases of malignant histiocytosis including 2 autopsy cases with special interest on their immunohistochemical characteristics. We report 3 cases of unusual immunohistochemical finding and postulate these cases may be a supportive evidence of the view that dendritic cells share common precursor with those of mononuclear phagocytic system. More accumulated cases in the future and careful analysis would be needed to answer the basic question about the origin of malignant histiocytosis.
我们回顾了18例恶性组织细胞增多症的临床和病理特征，其中包括2例尸检病例，并特别关注其免疫组化特征。我们报告了3例不寻常的免疫组化发现，并推测这些病例可能支持树突状细胞与单核吞噬系统细胞有共同前体这一观点。未来需要积累更多病例并进行仔细分析，以回答有关恶性组织细胞增多症起源的基本问题。
