Walter G F, Kleinert R, Kleinert G, Steiner H
Institute of Neuropathology, Medical College Hannover, FRG.
Clin Neuropathol. 1987 Jul-Aug;6(4):139-42.
Clinical, radiological and morphological findings in the case of a 79-year-old patient with a primary malignant histiocytosis of the brain are reported. The tumor was exclusively situated in the brain as proven by autopsy and was spreading on the inside of the lateral ventricles. The demonstration of atypical histiocytic cells in the CSF and the immunohistochemical demonstration of lysozyme, alpha 1-antitrypsin and alpha 1-antichymotrypsin which are typical for histiocytes, underline the histiocytic origin of the tumor.
报告了一名79岁原发性脑恶性组织细胞增多症患者的临床、放射学和形态学检查结果。尸检证实肿瘤仅位于脑内，并在侧脑室内扩散。脑脊液中发现非典型组织细胞，以及组织细胞典型的溶菌酶、α1抗胰蛋白酶和α1抗糜蛋白酶的免疫组化显示，均支持肿瘤的组织细胞起源。
