Bourbeau Kelsey, Moriarty Terence, Ayanniyi Akeisha, Zuhl Micah
Department of Health, Exercise, and Sports Sciences, University of New Mexico, Albuquerque, NM 87131, USA.
Department of Kinesiology, University of Northern Iowa, Cedar Falls, IA 50614, USA.
Behav Sci (Basel). 2020 Jul 14;10(7):116. doi: 10.3390/bs10070116.
Behavioral therapy (BT) and exercise are efficacious treatments for depression and anxiety when employed separately. The combination of BT and exercise (BT+Ex) may augment improvements but the combined effect of these therapies is not fully elucidated. The purpose of this meta-analysis was to determine if BT+Ex yielded a significant reduction in depression and anxiety symptoms compared to BT alone (BT). Randomized controlled studies published prior to September 2019 were searched among several databases (PUBMED, MEDLINE, PsychArticle, and Cochrane Central Register of Clinical Trials). Studies that measured depression and anxiety symptoms following BT+Ex vs. BT were extracted and analyzed. The effect of these therapies on depression and anxiety were analyzed. Subgroup analyses were performed to evaluate the effect of exercise intensity (moderate and high), exercise type (aerobic and combined exercise), and baseline levels of depression. The moderating effects of gender, age, and treatment duration were performed. Data were extracted from 18 studies (1686 participants, mean age = 47 years, 65% female). There was a significant effect of BT+Ex on symptoms of depression. The effect of BT+Ex was significant for moderate intensity exercise and elevated baseline levels of depression. Age moderated the effect for depression. There was a significant effect of BT+Ex on depressive symptoms in humans. Exercise intensity and elevated depressive symptoms may play a role in the effect of exercise.
行为疗法（BT）和运动单独使用时都是治疗抑郁症和焦虑症的有效方法。行为疗法与运动相结合（BT+Ex）可能会增强改善效果，但这些疗法的联合效果尚未完全阐明。本荟萃分析的目的是确定与单独使用行为疗法（BT）相比，BT+Ex是否能显著减轻抑郁和焦虑症状。在多个数据库（PUBMED、MEDLINE、PsychArticle和Cochrane临床试验中央注册库）中检索了2019年9月之前发表的随机对照研究。提取并分析了测量BT+Ex与BT后抑郁和焦虑症状的研究。分析了这些疗法对抑郁和焦虑的影响。进行亚组分析以评估运动强度（中等和高强度）、运动类型（有氧运动和综合运动）以及抑郁基线水平的影响。分析了性别、年龄和治疗持续时间的调节作用。数据来自18项研究（1686名参与者，平均年龄=47岁，65%为女性）。BT+Ex对抑郁症状有显著影响。BT+Ex对中等强度运动和较高抑郁基线水平有显著影响。年龄对抑郁影响有调节作用。BT+Ex对人类抑郁症状有显著影响。运动强度和较高的抑郁症状可能在运动效果中起作用。
