School of Pharmacy, Queen's University Belfast , Belfast, UK.
Expert Rev Med Devices. 2020 Oct;17(10):1007-1012. doi: 10.1080/17434440.2020.1792287. Epub 2020 Jul 17.
A pandemic is the worst-case scenario in the field of infectious diseases. Innovative technologies have the potential to address the challenges associated with the manufacture of personalized drug delivery systems, biosensors, and medical devices during a pandemic. 3D-Printing, microfluidics, and Microelectromechanical systems (MEMS) can provide an important part on this fight, as are cheap, easy to be operated, capable to provide rapid detection and monitoring of a disease, and deliver medicines.
This manuscript answers the question of how these emerging technologies can save lives during a pandemic by avoiding supply chain delays and also by providing rapid diagnostics, disease monitoring, or by offering personalized treatments. The manuscript covers recent approaches in the topic with a focus in manuscripts published in the last year and by emphasising recent regulatory considerations by regulatory agencies in the manufacturing of 3DP systems or other medical devices during COVID.
New manufacturing techniques are emerging with the ability to address the challenges associated with the development of medical devices or diagnostics, during a pandemic. Are many challenges in order to achieve this and especially in short times that are required under a pandemic attack, which will also be covered in this manuscript.
大流行是传染病领域最糟糕的情况。创新技术有可能解决与大流行期间个性化药物输送系统、生物传感器和医疗器械制造相关的挑战。3D 打印、微流控和微机电系统（MEMS）可以在这场战斗中提供重要的一环，因为它们便宜、易于操作、能够快速检测和监测疾病，并提供药物。
本文回答了这些新兴技术如何通过避免供应链延迟，以及通过提供快速诊断、疾病监测或提供个性化治疗，在大流行期间拯救生命的问题。本文涵盖了该主题的最新方法，重点是去年发表的论文，并强调了监管机构在 COVID 期间制造 3DP 系统或其他医疗器械时的最新监管考虑因素。
新的制造技术正在出现，它们有能力解决与医疗器械或诊断开发相关的挑战，在大流行期间。这需要克服许多挑战，尤其是在大流行袭击下所需的短时间内，本文也将涵盖这些挑战。
