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意大利在 COVID-19 大流行期间针对妊娠期糖尿病诊断的建议:意大利临床糖尿病学家协会 (AMD) 和意大利糖尿病学会 (SID)、糖尿病与妊娠研究组的立场声明。

Italian recommendations for the diagnosis of gestational diabetes during COVID-19 pandemic: Position statement of the Italian Association of Clinical Diabetologists (AMD) and the Italian Diabetes Society (SID), diabetes, and pregnancy study group.

机构信息

Interassociative Diabetes and Pregnancy Study Group, Italian Association of Diabetologists (AMD), Italian Diabetes Society (SID), Rome, Italy; Department of Medicine, Endocrinology and Metabolism, S. Maria della Misericordia University Hospital, Perugia, Italy.

Interassociative Diabetes and Pregnancy Study Group, Italian Association of Diabetologists (AMD), Italian Diabetes Society (SID), Rome, Italy; Italian Medicines Agency (AIFA), Rome, Italy.

出版信息

Nutr Metab Cardiovasc Dis. 2020 Aug 28;30(9):1418-1422. doi: 10.1016/j.numecd.2020.05.023. Epub 2020 May 29.

Abstract

AIM

In response to the COVID-19 pandemic, there is a need for substantial changes in the procedures for accessing healthcare services. Even in the current pandemic, we should not reduce our attention towards the diagnosis and treatment of GDM. The purpose of this document is to provide a temporary guide for GDM screening, replacing the current guidelines when it is not possible to implement standard GDM screening because of an unfavorable risk/benefit ratio for pregnant women or when usual laboratory facilities are not available.

DATA SYNTHESIS

At the first visit during pregnancy, we must exclude the presence of "Overt diabetes" in all women. The criteria for the diagnosis of overt diabetes are either fasting plasma glucose ≥126 mg/dL, or random plasma glucose ≥200 mg/dL, or glycated hemoglobin ≥6.5%. When the screening procedure (OGTT) cannot be safely performed, the diagnosis of GDM is acceptable if fasting plasma glucose is ≥ 92 mg/dL. In order to consider the impaired fasting glucose as an acceptable surrogate for the diagnosis of GDM, the fasting glucose measurement should be performed within the recommended time windows for the risk level (high or medium risk).

CONCLUSIONS

The changes to the screening procedure for GDM reported below are specifically produced in response to the health emergency of the COVID-19 pandemic. Therefore, these recommended changes should cease to be in effect and should be replaced by current national guidelines when the healthcare authorities declare the end of this emergency.

摘要

目的

应对 COVID-19 大流行,需要对获取医疗服务的程序进行重大改变。即使在当前大流行期间,我们也不应减少对 GDM 的诊断和治疗的关注。本文档的目的是提供 GDM 筛查的临时指南,以替代当前的指南,当由于对孕妇的风险/获益比不利或常规实验室设施不可用时,无法实施标准的 GDM 筛查。

数据综合

在妊娠期间的首次就诊时,我们必须排除所有女性都存在“显性糖尿病”。显性糖尿病的诊断标准为空腹血糖≥126mg/dL,或随机血浆葡萄糖≥200mg/dL,或糖化血红蛋白≥6.5%。当不能安全进行筛查程序(OGTT)时,如果空腹血糖≥92mg/dL,则可以接受 GDM 的诊断。为了将空腹血糖受损视为 GDM 诊断的可接受替代指标,空腹血糖测量应在高风险或中风险的建议时间窗口内进行。

结论

下面报告的 GDM 筛查程序的改变是专门针对 COVID-19 大流行的卫生紧急情况而产生的。因此,当卫生当局宣布结束此紧急情况时,这些建议的改变应停止生效,并应被当前的国家指南所取代。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4833/7258852/da4742760749/gr1_lrg.jpg

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