Oliva Margeaux, Hsu Karen, Alsamarai Sarah, Chavez Vincent de, Ferrara Lauren
Obstetrics and Gynecology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Obstetrics and Gynecology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
BMJ Case Rep. 2020 Jul 16;13(7):e236290. doi: 10.1136/bcr-2020-236290.
The clinical implications of COVID-19 in pregnancy remain unknown. While preliminary reports demonstrate that pregnant patients have a similar symptomatic presentation to the general population, the appropriate management and timing of delivery in these patients is still unclear, as pregnancy may impose additional risk factors and impede recovery in gravid patients. In this brief report, we present a case of COVID-19 in a pregnant patient with severe respiratory compromise, whose clinical status significantly improved after caesarean delivery. We also address the potential benefits of experimental therapy, including tocilizumab, a monoclonal antibody that targets interleukin-6 receptors.
新型冠状病毒肺炎(COVID-19)在妊娠期间的临床意义尚不清楚。虽然初步报告表明,孕妇的症状表现与普通人群相似,但这些患者的适当管理和分娩时机仍不明确,因为妊娠可能带来额外的风险因素,并阻碍孕妇康复。在本简要报告中,我们介绍了一例患有严重呼吸功能不全的COVID-19孕妇病例,其临床状况在剖宫产术后显著改善。我们还讨论了实验性治疗的潜在益处,包括托珠单抗,一种靶向白细胞介素-6受体的单克隆抗体。