哪些干预措施可有效预防多发性硬化症患者跌倒？Cochrane 综述摘要及评论。
Which interventions are effective in preventing falls in people with multiple sclerosis? A Cochrane Review summary with commentary.
机构信息
Department of Rehabilitation and Australian Rehabilitation Research Centre, Royal Melbourne Hospital, Parkville, VIC, Australia.
Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Parkville, VIC, Australia.
出版信息
NeuroRehabilitation. 2020;47(1):79-82. doi: 10.3233/NRE-209005.
BACKGROUND
Falls are common and serious health concern in people with multiple sclerosis (MS). Various types of falls prevention interventions are currently investigated in people with MS.
OBJECTIVE
To assess the effectiveness of interventions to reduce falls in people with MS.
METHODS
To summarize falls prevention interventions from the published Cochrane Review "Interventions for preventing falls in people with multiple sclerosis" conducted by Hayes et al. Best available evidence was discussed from the rehabilitation perspective.
RESULTS
Overall 13 RCTs with 839 participants were included. The interventions evaluated included: exercise, education, and functional electrical stimulation alone or in combination. Majority of the included studies demonstrated high risk of bias. The findings suggest that the evidence was uncertain regarding the effects of evaluated interventions on preventing or reducing falls.
CONCLUSIONS
The evidence for any falls prevention interventions in people with MS is sparse and uncertain, and more robust studies are needed.
背景
多发性硬化症（MS）患者常发生严重的跌倒事件，这是一个值得关注的健康问题。目前，人们正在对各种类型的跌倒预防干预措施进行研究。
目的
评估干预措施对 MS 患者跌倒的预防效果。
方法
总结由 Hayes 等人进行的已发表的 Cochrane 综述“多发性硬化症患者跌倒预防干预措施”中的跌倒预防干预措施。从康复角度讨论了最佳现有证据。
结果
共纳入了 13 项 RCT，涉及 839 名参与者。评估的干预措施包括：单独或联合应用运动、教育和功能性电刺激。大多数纳入的研究存在高偏倚风险。结果表明，评估干预措施对预防或减少跌倒的效果的证据尚不确定。
结论
MS 患者任何跌倒预防干预措施的证据都很少且不确定，需要进行更有力的研究。
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