Suppr超能文献

分化型甲状腺癌合并气管侵犯的长期预后:15 年经验。

Long-term outcomes of differentiated thyroid cancers with tracheal invasion: A 15-year experience.

机构信息

Department of Surgical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, India.

出版信息

Indian J Cancer. 2020 Oct-Dec;57(4):398-404. doi: 10.4103/ijc.IJC_456_19.

Abstract

BACKGROUND

Tracheal invasion is reported to occur in approximately one-third of the patients of locally advanced thyroid cancers. There is a paucity of data in literature with regard to the long-term outcomes of thyroid cancers with tracheal invasion.

METHODS

A total of 37 patients from our tertiary care center underwent radical surgery for tracheal involvement for differentiated thyroid cancers between the years 2002 and 2016. The variables pertaining to the demographics, clinical presentation, imaging, operative details and histopathology reports were captured from the patient's case records and analyzed.

RESULTS

Among the 37 patients, there were 21 males and 16 females. Majority of the patients (56.8%) were >55 years of age. Surgery (tracheal resection) was performed in the primary setting in 29 patients, whereas it was performed in a recurrent setting in 8 patients. As per the Shin classification, 3 patients belonged to Shin stage 1, 3 to Shin stage 2, 16 patients to Shin stage 3 and 15 patients to Shin stage 4. There was no 30 day postoperative mortality in our cohort. The median follow-up of our cohort was 175 months. The 5-, 10-, and the 15-year overall survivals of the entire cohort were 81.7%, 47.8%, and 35.9%, respectively.

CONCLUSION

Our series shows favorable long-term oncological outcomes of selected patients of thyroid cancers with tracheal resection and adds to the limited long-term data available in literature.

摘要

背景

据报道,局部晚期甲状腺癌患者中约有三分之一发生气管侵犯。关于气管侵犯的甲状腺癌的长期预后,文献中数据有限。

方法

我们的三级护理中心共有 37 名患者在 2002 年至 2016 年间因分化型甲状腺癌接受了根治性手术以治疗气管受累。从患者的病历中提取并分析了与人口统计学、临床表现、影像学、手术细节和组织病理学报告相关的变量。

结果

在 37 名患者中,有 21 名男性和 16 名女性。大多数患者(56.8%)年龄>55 岁。29 名患者在初次手术时进行了手术(气管切除术),而 8 名患者在复发时进行了手术。根据 Shin 分期,3 名患者属于 Shin 分期 1,3 名患者属于 Shin 分期 2,16 名患者属于 Shin 分期 3,15 名患者属于 Shin 分期 4。我们的队列中没有术后 30 天死亡病例。我们队列的中位随访时间为 175 个月。整个队列的 5 年、10 年和 15 年总生存率分别为 81.7%、47.8%和 35.9%。

结论

我们的系列研究表明,对于接受气管切除术的甲状腺癌患者,选择合适的患者可以获得良好的长期肿瘤学结果,并为文献中有限的长期数据提供了补充。

相似文献

9
Clinicopathologic study of thyroid carcinoma infiltrating the trachea.甲状腺癌侵犯气管的临床病理研究
Cancer. 1985 Dec 15;56(12):2843-8. doi: 10.1002/1097-0142(19851215)56:12<2843::aid-cncr2820561221>3.0.co;2-q.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验