Clinic of Pediatrics, 1st Faculty of Medicine, Charles University in Prague and Institute of Postgraduate Medical Education, Thomayer Hospital, Prague 4, Czech Republic.
Department of Epidemiology,2nd Faculty of Medicine, Charles University in Prague and University Hospital Motol, Prague 5, Czech Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021 Sep;165(3):277-282. doi: 10.5507/bp.2020.025. Epub 2020 Jul 7.
Comparision of the incidence of cervical lymphadenitis caused by nontuberculous mycobacteria in two equal time periods before and after the ending of widespread calmetization (tuberculosis vaccination). Backgroung. From 2011 to 2018, 89 children were registered in the Tuberculosis Register with cervical lymphadenitis caused by nontuberculous mycobacteria, as confirmed by cultivation. In the majority of cases, the infection was caused by a mycobacterium belonging to the Mycobacterium avium complex. Only 7 cases of cervical lymphadenitis of the same etiology were registered during the same time interval between 2003 and 2010. The authors consider the ending of widespread calmetization (tuberculosis vaccination) in 2010 to be the main cause of the growing incidence.
A comparison of data for the period 2003-2018 about cases of the illness caused by atypical mycobacteria as reported in the Tuberculosis Register.
The average incidence per year in the first interval was 0.04/100 000 children and in the second interval 0.53/100 000 children. During the second time interval, there was an increase from 0.14/100 000 children in 2011 to 1.40/100 000 children in 2018. While the incidence during the first time interval did not show any time trend (P=0.885), the year 2010 marks a significant turning point, with growth during the second interval being highly statistically significant (P<0.001).
比较广泛开展卡介苗（结核病疫苗）接种结束前后两个相等时间段内非结核分枝杆菌引起的颈淋巴结炎的发病率。背景。2011 年至 2018 年，有 89 名儿童在结核病登记处登记患有非结核分枝杆菌引起的颈淋巴结炎，经培养证实。在大多数情况下，感染是由分枝杆菌属分枝杆菌复合群引起的。在 2003 年至 2010 年的同一时间段内，仅登记了 7 例相同病因的颈淋巴结炎。作者认为 2010 年广泛开展卡介苗接种的结束是发病率增长的主要原因。
比较 2003-2018 年结核病登记处报告的非典型分枝杆菌引起的疾病数据。
第一个时间段的年平均发病率为 0.04/100000 名儿童，第二个时间段为 0.53/100000 名儿童。在第二个时间段，发病率从 2011 年的 0.14/100000 名儿童增加到 2018 年的 1.40/100000 名儿童。虽然第一个时间段的发病率没有显示任何时间趋势（P=0.885），但 2010 年标志着一个重要的转折点，第二个时间段的增长具有高度统计学意义（P<0.001）。
