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Basic Mechanisms of JAK Inhibition.

作者信息

Lin Chung Ma, Cooles Faye Ah, Isaacs John D

机构信息

Translational and Clinical Research Institute, Newcastle University and Musculoskeletal Unit, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.

出版信息

Mediterr J Rheumatol. 2020 Jun 11;31(Suppl 1):100-104. doi: 10.31138/mjr.31.1.100. eCollection 2020 Jun.

DOI:10.31138/mjr.31.1.100
PMID:32676567
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7361186/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f2a/7361186/a8b2149daddc/MJR-31-Suppl-1-100-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f2a/7361186/a8b2149daddc/MJR-31-Suppl-1-100-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f2a/7361186/a8b2149daddc/MJR-31-Suppl-1-100-g001.jpg

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Comparison of baricitinib, upadacitinib, and tofacitinib mediated regulation of cytokine signaling in human leukocyte subpopulations.比较巴瑞替尼、乌帕替尼和托法替尼对人白细胞亚群细胞因子信号转导的调控作用。
Arthritis Res Ther. 2019 Aug 2;21(1):183. doi: 10.1186/s13075-019-1964-1.
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JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis.JAK 抑制剂。类风湿关节炎之外,免疫介导性疾病领域的新玩家。
Rheumatology (Oxford). 2019 Feb 1;58(Suppl 1):i43-i54. doi: 10.1093/rheumatology/key276.
3
Selective JAKinibs: Prospects in Inflammatory and Autoimmune Diseases.
系统性红斑狼疮治疗的进展
Nat Rev Drug Discov. 2025 Jul 17. doi: 10.1038/s41573-025-01242-0.
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A systematic literature review of Janus kinase inhibitors for the treatment of systemic sclerosis.关于用于治疗系统性硬化症的 Janus 激酶抑制剂的系统文献综述。
J Scleroderma Relat Disord. 2025 May 22:23971983251342697. doi: 10.1177/23971983251342697.
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A Case Series and Review of Febrile-Infection Related Epilepsy Syndrome (FIRES).发热感染相关癫痫综合征(FIRES)的病例系列报告及综述
Children (Basel). 2025 Apr 10;12(4):485. doi: 10.3390/children12040485.
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Interindividual variability and its impact on the effectiveness of Janus kinase inhibitors in rheumatoid arthritis treatment.个体间变异性及其对类风湿关节炎治疗中Janus激酶抑制剂疗效的影响。
Front Med (Lausanne). 2025 Mar 28;12:1512501. doi: 10.3389/fmed.2025.1512501. eCollection 2025.
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