A phosphoprotein helps lipid droplets stay in shape.
作者信息
Spiering Martin J
出版信息
J Biol Chem. 2020 Jul 17;295(29):10078-10080. doi: 10.1074/jbc.CL120.014813.
Abstract
摘要
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本文引用的文献
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The role of lipid droplets in metabolic disease in rodents and humans.脂滴在啮齿动物和人类代谢性疾病中的作用。
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Differential pattern of lipid droplet-associated proteins and de novo perilipin expression in hepatocyte steatogenesis.肝细胞脂肪变性中脂滴相关蛋白的差异模式及新生周脂素表达
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Perilipin A mediates the reversible binding of CGI-58 to lipid droplets in 3T3-L1 adipocytes.perilipin A介导CGI-58与3T3-L1脂肪细胞中脂滴的可逆结合。
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Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma.脂质小滴相关蛋白S3-12和围脂滴蛋白在脂肪组织中的表达受过氧化物酶体增殖物激活受体γ的调控。
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Involvement of a cGMP-dependent pathway in the natriuretic peptide-mediated hormone-sensitive lipase phosphorylation in human adipocytes.环磷酸鸟苷（cGMP）依赖性途径参与利钠肽介导的人脂肪细胞中激素敏感性脂肪酶的磷酸化过程。
J Biol Chem. 2003 Dec 5;278(49):48617-26. doi: 10.1074/jbc.M303713200. Epub 2003 Sep 10.
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Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation.perilipin A在脂解激活过程中对激素敏感性脂肪酶的转位至关重要。
J Cell Biol. 2003 Jun 23;161(6):1093-103. doi: 10.1083/jcb.200210169. Epub 2003 Jun 16.
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Identification of genes potentially involved in rupture of human atherosclerotic plaques.鉴定可能与人类动脉粥样硬化斑块破裂相关的基因。
Circ Res. 2001 Sep 14;89(6):547-54. doi: 10.1161/hh1801.096340.
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Phosphorylation of PDE3B by phosphatidylinositol 3-kinase associated with the insulin receptor.磷脂酰肌醇3激酶与胰岛素受体相关，使磷酸二酯酶3B发生磷酸化。
J Biol Chem. 2000 Apr 7;275(14):10093-8. doi: 10.1074/jbc.275.14.10093.
9
Dephosphorylation of perilipin by protein phosphatases present in rat adipocytes.大鼠脂肪细胞中存在的蛋白磷酸酶对 perilipin 的去磷酸化作用。
FEBS Lett. 1998 Sep 11;435(1):125-9. doi: 10.1016/s0014-5793(98)01052-7.
10
Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3-L1 adipocytes.脂联素A和B的过表达会阻碍肿瘤坏死因子α提高3T3-L1脂肪细胞中脂肪分解的能力。
J Biol Chem. 1998 Sep 18;273(38):24665-9. doi: 10.1074/jbc.273.38.24665.
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