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改良大脑半球切除术治疗癫痫:10例早期结果

Modified hemispherectomy for epilepsy: early results in 10 cases.

作者信息

Beardsworth E D, Adams C B

机构信息

Department of Clinical Neuropsychology, Radcliffe Infirmary, Oxford, United Kingdom.

出版信息

Br J Neurosurg. 1988;2(1):73-84. doi: 10.3109/02688698808999662.

Abstract

Early outcome results for 10 cases of modified hemispherectomy are presented. All patients had a history of infantile hemiplegia and intractable epilepsy. Pre- and postoperative measures for seizures and motor and cognitive and behavioural functioning are described. Early results are encouraging with no mortality and a low rate of complications. There was a complete cessation of seizures in seven patients and a considerable reduction in seizure frequency in two. Motor functioning was largely unaffected. Behaviour problems tended to improve at the cessation of seizures. IQ scores did not deteriorate as a consequence of operation and some patients showed considerable gains in IQ with the passage of time. Details of cognitive functioning are described.

摘要

本文介绍了10例改良大脑半球切除术的早期结果。所有患者均有婴儿偏瘫和难治性癫痫病史。描述了术前和术后癫痫发作、运动、认知和行为功能的测量情况。早期结果令人鼓舞,无死亡病例,并发症发生率低。7例患者癫痫完全停止,2例患者癫痫发作频率显著降低。运动功能基本未受影响。癫痫停止后行为问题往往有所改善。智商分数并未因手术而恶化,一些患者随着时间推移智商有显著提高。文中描述了认知功能的细节。

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