Hamdi S, Bendayan M, Huyghe E, Soufir J-C, Amar E, El Osta R, Plotton I, Delalande C, Perrin J, Leroy C, Bouker A, Pons H, Lejeune H, Robin G, Boitrelle F
Société d'Andrologie de langue Française (SALF), http://www.salf.fr.
Université de Toulouse, UPS, Groupe de Recherche en Fertilité Humaine (EA 3694, Human Fertility Research Group), 330 avenue de Grande Bretagne, 31059 Toulouse, France.
Basic Clin Androl. 2020 Jul 13;30:10. doi: 10.1186/s12610-020-00106-4. eCollection 2020.
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) metamorphosed our medical practice. In early June 2020, more than 6,400,000 COVID-19 (coronavirus-19 disease) cases were diagnosed across the world and more than 380,000 deaths were linked to COVID-19. Many medical symptoms of COVID-19 were reported. We will focus, here, on potential impacts of COVID-19 on men's andrological health. Our society (French-speaking society of andrology, SALF) also emitted some recommendations in the andrological management of men infected by SARS-CoV-2. First, considering the fever and the potential presence of SARS-CoV2 in semen, SALF recommends waiting for 3 months (duration of one spermatogenesis cycle and epididymal transit) before re-starting ART in the case of men diagnosed COVID-19 positive. Whatever the nature of testosterone and COVID-19 relationships, we recommend an andrological examination, sperm parameters, and hormonal evaluation at the time of the COVID-19 is diagnosed, and several months later. Furthermore, we are concerned by the potential morbid-mortality of the COVID-19, which mainly affects men. This "andrological bias", if proven, must be reduced by specific andrological diagnosis, therapeutic and prophylactic measures. Research in this direction must be substantiated and financially supported over the next few months (years).
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)改变了我们的医疗实践。2020年6月初,全球确诊了超过640万例2019冠状病毒病(COVID-19)病例,超过38万人死亡与COVID-19相关。报告了许多COVID-19的医学症状。在此,我们将重点关注COVID-19对男性生殖健康的潜在影响。我们的协会(法语国家男科学会,SALF)也发布了一些关于感染SARS-CoV-2的男性的男科管理建议。首先,考虑到发热以及精液中可能存在SARS-CoV-2,SALF建议确诊为COVID-19阳性的男性在重新开始抗逆转录病毒治疗(ART)之前等待3个月(一个精子发生周期和附睾运输的持续时间)。无论睾酮与COVID-19关系的性质如何,我们建议在确诊COVID-19时以及数月后进行男科检查、精子参数和激素评估。此外,我们担心主要影响男性的COVID-19的潜在致病死亡率。这种“男科偏差”如果得到证实,必须通过特定的男科诊断、治疗和预防措施来减少。在未来几个月(几年),必须对这一方向的研究提供充实的内容和资金支持。