Takia Lalit, Patra Nilamani, Nallasamy Karthi, Saini Lokesh, Suthar Renu, Angurana Suresh K, Jayashree Muralidharan
Division of Pediatric Critical Care, Department of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Division of Pediatric Neurology, Department of Pediatrics, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
J Pediatr Intensive Care. 2020 Sep;9(3):222-224. doi: 10.1055/s-0040-1705182. Epub 2020 Mar 6.
Acute necrotizing encephalopathy of childhood (ANEC) is an uncommon and fulminant complication of seasonal influenza infection associated with high mortality and poor neurological outcome. We report a 4.5-year-old female who had pneumonia, ANEC, and raised intracranial pressure (ICP) with polymerase chain reaction proven H1N1 infection. Management included mechanical ventilation, invasive monitoring and control of ICP, oseltamivir, methylprednisolone, and supportive care in pediatric intensive care unit. She survived with poor neurological status at discharge.
儿童急性坏死性脑病（ANEC）是季节性流感感染的一种罕见且暴发性并发症，与高死亡率和不良神经学预后相关。我们报告一名4.5岁女性，她患有肺炎、ANEC，且颅内压（ICP）升高，聚合酶链反应证实感染H1N1。治疗包括机械通气、有创监测和ICP控制、奥司他韦、甲泼尼龙，以及在儿科重症监护病房的支持治疗。她出院时神经状态不佳但存活了下来。
