Rabies epidemiology, natural barriers and fox vaccination.

Rabies in Central Europe is maintained and spread by red foxes (Vulpes vulpes). The epidemiology is explained by a variety of parameters of the main host. Certain natural and artificial topographic features may function as barriers to the spread of the virus within fox populations. Taking into account epidemiological barriers greatly facilitated the strategic application of oral immunization of foxes for freeing Switzerland from rabies.