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融合是否会影响连续两水平杂交手术中相邻颈椎间盘置换的前方骨丢失?

Does Fusion Affect Anterior Bone Loss in Adjacent Cervical Disc Arthroplasty in Contiguous Two-Level Hybrid Surgery?

机构信息

Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China.

Department of Orthopedic Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

World Neurosurg. 2020 Nov;143:e127-e135. doi: 10.1016/j.wneu.2020.07.054. Epub 2020 Jul 17.

DOI:10.1016/j.wneu.2020.07.054
PMID:32688043
Abstract

OBJECTIVE

To investigate whether anterior bone loss (ABL) in cervical discarthroplasty (CDA) in 2-level hybrid surgery (HS) is affected by adjacent fusion in vivo compared with 1-level CDA alone.

METHODS

A total of 180 patients undergoing either a 1-level CDA or contiguous 2-level HS were retrospectively reviewed. The clinical and radiographic outcomes were collected preoperatively and at routine postoperative intervals of 1 week, 3, 6, and 12 months, and at the last follow-up. The initial and postoperative radiographs were compared to determine the incidence and degree of ABL.

RESULTS

ABL was identified in 68.7% of CDA cases (37.9% mild, 34.8% moderate, and 27.3% severe) and 44.0% of HS cases (54.1% mild, 27.0% moderate, and 18.9% severe). Sex, age, bone mineral density, operation time, blood loss, postoperative alignment, and range of movement at the arthroplasty segment were not related to the incidence of ABL. According to the logistic regression analysis results, ABL showed a significant correlation with the surgery type and body mass index. However, there was no significant difference in the incidence and degree of ABL with or without an adjacent fusion level. Compared with preoperative values, clinical outcome scores significantly improved after surgery in both the HS and CDA groups. No definite clinical effect associated with ABL was found.

CONCLUSIONS

ABL was common in both CDA and HS. Although HS had a lower incidence rate and degree than did CDA, the fusion location in HS did not affect the ABL of adjacent CDA.

摘要

目的

研究颈椎间盘置换术(CDA)在 2 级杂交手术(HS)中与单独 1 级 CDA 相比,是否会因相邻融合而导致前骨丢失(ABL)。

方法

回顾性分析了 180 例接受 1 级 CDA 或连续 2 级 HS 的患者。收集术前及术后 1 周、3、6、12 个月和最后随访时的临床和影像学结果。比较术前和术后的 X 线片,确定 ABL 的发生率和程度。

结果

CDA 病例中 ABL 发生率为 68.7%(轻度 37.9%,中度 34.8%,重度 27.3%),HS 病例中 ABL 发生率为 44.0%(轻度 54.1%,中度 27.0%,重度 18.9%)。性别、年龄、骨密度、手术时间、出血量、术后对线、置换节段活动度与 ABL 的发生率无关。Logistic 回归分析结果表明,ABL 与手术类型和体重指数显著相关。然而,有无相邻融合节段,ABL 的发生率和程度无显著差异。与术前相比,HS 和 CDA 组术后临床评分均显著改善。未发现 ABL 与明确的临床疗效相关。

结论

CDA 和 HS 中 ABL 均较常见。虽然 HS 的发生率和程度均低于 CDA,但 HS 中的融合位置并不影响相邻 CDA 的 ABL。

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