Departamento de Neurocirugía, Hospital Universitario Fundación Jiménez Díaz, Madrid, España.
Departamento de Neurocirugía, Hospital Universitari Bellvitge, L'Hospitalet de Llobregat (Barcelona), España.
Neurocirugia (Astur : Engl Ed). 2020 Nov-Dec;31(6):289-298. doi: 10.1016/j.neucir.2020.06.001. Epub 2020 Jul 18.
Glioblastoma (GBM) treatment starts in most patients with surgery, either resection surgery or biopsy, to reach a histology diagnose. Multidisciplinar team, including specialists in brain tumors diagnose and treatment, must make an individualize assessment to get the maximum benefit of the available treatments.
Experts in each GBM treatment field have briefly described it based in their experience and the reviewed of the literature.
Each area has been summarized and the consensus of the brain tumor group has been included at the end.
GBM are aggressive tumors with a dismal prognosis, however accurate treatments can improve overall survival and quality of life. Neurosurgeons must know treatment options, indications and risks to participate actively in the decision making and to offer the best surgical treatment in every case.
胶质母细胞瘤(GBM)的治疗通常从手术开始,手术方式包括肿瘤切除术或活检术,以获得组织学诊断。多学科团队,包括脑肿瘤诊断和治疗方面的专家,必须进行个体化评估,以从现有治疗方法中获得最大收益。
每位 GBM 治疗领域的专家根据自己的经验和文献回顾简要描述了治疗方法。
每个领域都进行了总结,并在最后纳入了脑肿瘤专家组的共识。
GBM 是具有侵袭性和预后不良的肿瘤,然而准确的治疗可以提高总生存率和生活质量。神经外科医生必须了解治疗方案、适应证和风险,以积极参与决策,并在每种情况下提供最佳的手术治疗。