Department of Urology, Mayo Clinic, Rochester, MN, USA.
Institute for Urologic Excellence, La Quinta, CA, USA.
Int J Impot Res. 2020 Dec;33(8):785-792. doi: 10.1038/s41443-020-0326-5. Epub 2020 Jul 21.
Inflatable penile prosthesis (IPP) infections are undeniably devastating for patient and surgeon alike. While less common in this modern era, the landscape of prosthesis infection is shifting. Continued examination of risk factors for infection and re-evaluation of common practices remain critical should we aim to advance the field. Quality research on this topic is limited by several factors, among which small sample size and lack of coordinated effort pose the most precarious of challenges. Nonetheless, careful analysis of available data in conjuncture with judicious utilization of established research from other prosthetic fields can help us better grasp the issue at hand. In this review, we aim to do exactly that-to examine available evidence in an effort to discern fact from fiction. In this first part of the three part series, we aim to summarize our understanding of the pathogenesis behind prosthesis infections, explore known preoperative risk factors, and discuss intraoperative considerations for infection prevention. In the second part of this series, we will examine the game changing effect of infection retardant implant coatings. Part three of the series details postoperative prevention strategies, reviews salvage techniques, and discusses additional key considerations.
可充气阴茎假体 (IPP) 感染对患者和外科医生来说都是毁灭性的。虽然在现代这个时代不太常见，但假体感染的情况正在发生变化。如果我们要推动这一领域的发展，继续检查感染的危险因素并重新评估常见做法仍然至关重要。由于多种因素的限制，关于这个主题的高质量研究是有限的，其中样本量小和缺乏协调努力构成了最危险的挑战。尽管如此，仔细分析现有数据并明智地利用其他假体领域的既定研究，可以帮助我们更好地掌握当前的问题。在这篇综述中，我们的目标正是如此——仔细分析现有证据，以辨别事实和虚构。在这个三部分系列的第一部分中，我们旨在总结我们对假体感染背后发病机制的理解，探讨已知的术前危险因素，并讨论预防感染的术中注意事项。在本系列的第二部分中，我们将研究感染抑制植入物涂层的改变游戏规则的效果。第三部分详细介绍了术后预防策略，回顾了挽救技术，并讨论了其他关键注意事项。
