Pop Raluca Maria, Trifa Adrian Pavel, Popolo Ada, Chedea Veronica Sanda, Militaru Claudia, Bocsan Ioana Corina, Buzoianu Anca Dana
Iuliu Hatieganu University of Medicine and Pharmacy, Department of Pharmacology, Toxicology and Clinical Pharmacology, Cluj Napoca, Romania.
Iuliu Hatieganu University of Medicine and Pharmacy, Department of Genetics, Cluj Napoca, Romania.
Iran J Basic Med Sci. 2020 Jun;23(6):699-713. doi: 10.22038/ijbms.2020.37734.8978.
Over the past 20 years, increasing interest in the use of medicinal plants as alternative or adjuvant treatments of several chronic diseases was observed. Accordingly, or black cumin, a medicinal plant rich in bioactive compounds, has been used worldwide for food purposes or in traditional medicines. This paper aims to reveal potential as adjunct treatment in cardiovascular diseases, diabetes, and hematological malignancies, due to their increasing prevalence and difficult management in everyday life.
Databases like PubMed, Web of Science, Science Direct, Scopus, and Google Scholar were used to search the literature data. Keywords like anti-inflammatory effect, anti-oxidant effect, antihypertensive effects, hypolipidemic effects and hematological malignancies were used in combination with
Because of its numerous pharmacological actions, but especially for its anti-oxidant and anti-inflammatory properties, and studies demonstrated positive effect against diabetes, hypertension, and hypercholesterolemia, all of them associated to cardiovascular diseases progression. Also, it was proved to have marked anti-proliferative, cytotoxic, pro-apoptotic, and anti-metastatic effects, in both solid cancers and hematological malignancies.
used as complementary treatment to classical medications can improve the management of several chronic diseases.
在过去20年中，人们越来越关注将药用植物用作多种慢性疾病的替代或辅助治疗方法。因此，黑孜然这种富含生物活性化合物的药用植物，已在全球范围内用于食品或传统药物中。本文旨在揭示其在心血管疾病、糖尿病和血液系统恶性肿瘤中作为辅助治疗的潜力，因为这些疾病的患病率不断上升且在日常生活中难以管理。
使用PubMed、科学网、科学Direct、Scopus和谷歌学术等数据库来搜索文献数据。将抗炎作用、抗氧化作用、降压作用、降血脂作用和血液系统恶性肿瘤等关键词与……结合使用。
由于其众多的药理作用，尤其是其抗氧化和抗炎特性，多项研究表明其对糖尿病、高血压和高胆固醇血症具有积极作用，所有这些都与心血管疾病的进展相关。此外，在实体癌和血液系统恶性肿瘤中，它都被证明具有显著的抗增殖、细胞毒性、促凋亡和抗转移作用。
用作传统药物的补充治疗可以改善几种慢性疾病的管理。
