Rump S, Kowalczyk M, Penczek P
Department of Pharmacology, Military Institute of Hygiene and Epidemiology, Warszawa, Poland.
Pol J Pharmacol Pharm. 1988 Nov-Dec;40(6):585-92.
A new assay of afterdischarge pattern evaluation is presented, using computerized automatic analysis where procedure of data reduction, known as syntactic analysis, was involved. Effects of phenobarbital and diazepam on afterdischarge pattern were also studied. Adopting Kalman filters technique and Markov chain midel a multi-channel analysis was performed. Significant differences between effects of two tested drugs on seizure activity propagation were found.
本文介绍了一种新的放电后模式评估测定法,该方法使用计算机自动分析,其中涉及数据简化程序,即句法分析。还研究了苯巴比妥和地西泮对放电后模式的影响。采用卡尔曼滤波技术和马尔可夫链模型进行了多通道分析。发现两种受试药物对癫痫发作活动传播的影响存在显著差异。