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肺炎球菌疫苗在成人哮喘患者中的应用。

Pneumococcal Vaccine in Adult Asthma Patients.

机构信息

Ipswich Hospital, East Suffolk and North Essex NHS Foundation Trust, Ipswich, UK.

Ysbyty Gwynedd, Betsi Cadwaladr University Health Board, Bangor, UK.

出版信息

Adv Exp Med Biol. 2021;1289:55-62. doi: 10.1007/5584_2020_562.

DOI:10.1007/5584_2020_562
PMID:32696445
Abstract

Streptococcus pneumoniae is the most frequent source of community-acquired bacterial pneumonia in adults. Respiratory tract infections are the foremost reasons for asthma exacerbations. The World Health Organization and the Centers for Disease Control and Prevention consider asthma a clear indication for pneumococcal vaccination. The aim of this study was to determine the extent to which adult patients with asthma in Poland adhere to a schedule of recommended pneumococcal vaccinations. In addition, the study attempted to assess the source of the patient knowledge on vaccination and the plausible determents for vaccination. The study was conducted among patients at specialist outpatient clinics in the form of an anonymous survey that contained questions about asthma, vaccines, and the knowledge and motivations. A total of 214 patients (149 females and 65 males) of the mean age of 52 ± 17 years were interviewed. A staggering 93% of patients did not receive pneumococcal vaccination, and only 24% of patients were aware of the need for this vaccine. Age, gender, and education did not affect whether patients chose to receive the vaccine. The most often quoted reason for not receiving the vaccine was lack of information, followed by lack of faith in vaccine efficacy, and the fear of adverse effects. From the standpoint of health hazard stemming from prophylaxis avoidance, it appears paramount to educate asthmatic patients on the benefits of receiving pneumococcal vaccination.

摘要

肺炎链球菌是成人社区获得性细菌性肺炎最常见的病原体。呼吸道感染是哮喘恶化的首要原因。世界卫生组织和疾病控制与预防中心认为哮喘是接种肺炎球菌疫苗的明确指征。本研究旨在确定波兰哮喘成年患者遵循推荐肺炎球菌疫苗接种计划的程度。此外,该研究试图评估患者对疫苗接种的了解来源以及疫苗接种的可能决定因素。该研究以匿名调查的形式在专科门诊的患者中进行,其中包含有关哮喘、疫苗接种以及知识和动机的问题。共采访了 214 名患者(149 名女性和 65 名男性),平均年龄为 52 ± 17 岁。令人震惊的是,93%的患者未接种肺炎球菌疫苗,只有 24%的患者知道需要接种这种疫苗。年龄、性别和教育程度并未影响患者是否选择接种疫苗。未接种疫苗的最常见原因是缺乏信息,其次是对疫苗有效性缺乏信心,以及对不良反应的恐惧。从预防措施避免带来的健康危害角度来看,对哮喘患者进行有关接种肺炎球菌疫苗益处的教育似乎至关重要。

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本文引用的文献

1
[Profile of adults suffering from asthma in Poland--results of PulmoScreen study].[波兰成年哮喘患者概况——PulmoScreen研究结果]
Pneumonol Alergol Pol. 2012;80(5):402-11.