Suppr超能文献

膝关节血友病性关节积血的非血友病人群的当前管理综述。

A Review of Current Management of Knee Hemarthrosis in the Non-Hemophilic Population.

机构信息

Rutgers New Jersey Medical School, Newark, NJ, USA.

Hospital for Special Surgery, New York, NY, USA.

出版信息

Cartilage. 2021 Dec;13(1_suppl):116S-121S. doi: 10.1177/1947603520942937. Epub 2020 Jul 22.

Abstract

The knee joint is one of the most frequently injured joints in the body, and the resulting injury may often lead to the presence of a bloody effusion, or hemarthrosis. The acute management of this condition can have long-lasting implications, and may ultimately result in the early onset of osteoarthritis in this population. Heme, a breakdown product of erythrocytes, and associated pro-inflammatory mediators, are known to have deleterious interactions with cartilage and synovium. The presence of blood in a joint following injury can precipitate these effects and accelerate the degenerative changes in the joint. Currently, there is no consensus on the optimal management of a traumatic knee joint injury with a hemarthrosis. Nontraumatic hemarthosis, seen most commonly in hemophilia patients, has a set of established guidelines that does not routinely recommend drainage of the joint. This article presents a rationale for joint aspiration to minimize the harmful effects of blood following traumatic hemarthrosis.

摘要

膝关节是人体最常受伤的关节之一,受伤后常常会导致关节内积血,即血 肿。这种情况的急性处理会产生长期影响,最终可能导致该人群中骨关节炎的早发。众所周知,红细胞的降解产物——血红素及其相关促炎介质与软骨和滑膜有有害的相互作用。受伤后关节内出血会引发这些影响,并加速关节的退行性变化。目前,对于创伤性膝关节损伤伴血 肿,尚无关于最佳处理方法的共识。非创伤性血 肿最常见于血友病患者,有一套既定的指南,不常规建议引流关节。本文提出了关节抽吸的基本原理,以最大限度地减少创伤性血 肿后血液的有害影响。

相似文献

7
The knee joint in hemophilia.血友病中的膝关节。
Orthop Clin North Am. 1979 Jan;10(1):139-73.

引用本文的文献

本文引用的文献

3
Evidence-Based Management of the Knee in Hemophilia.血友病膝关节的循证管理
JBJS Rev. 2017 Aug;5(8):e12. doi: 10.2106/JBJS.RVW.16.00100.
7
Advances and challenges in hemophilic arthropathy.血友病性关节病的进展与挑战
Semin Hematol. 2016 Jan;53(1):10-9. doi: 10.1053/j.seminhematol.2015.10.005. Epub 2015 Oct 26.
9
Red Blood Cells Store and Release Interleukin-33.红细胞储存并释放白细胞介素-33。
J Investig Med. 2015 Aug;63(6):806-10. doi: 10.1097/JIM.0000000000000213.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验