Montane I, McCollough N C, Lian E C
J Bone Joint Surg Am. 1986 Feb;68(2):210-6.
Synovectomy of the knee for the control of recurrent hemarthrosis was performed in thirteen patients with hemophilic arthropathy. Preoperatively, all patients had experienced an average of three bleeding episodes into the affected joint per month, and had been unresponsive to at least six months of medical management. Radiographically, all knees had either Stage-II or Stage-III hemophilic arthropathy. The average age of the patients at the time of synovectomy was sixteen years and the average length of follow-up was 7.3 years (range, two to eleven years and seven months). Although the motion of the knee remained unchanged postoperatively in two patients, ten patients had an average loss of 41 degrees. One patient eventually required an arthrodesis. Radiographically, there was slight further joint deterioration after synovectomy, and no knee progressed beyond Stage-III hemophilic arthropathy. Only one patient in our series had a recurrent spontaneous hemarthrosis of the synovectomized knee, although two others had traumatic bleeding episodes. The complications included three immediate postoperative hemarthrosis requiring surgical evacuation, isoimmune hemolytic anemia in one patient, patellofemoral adhesions in two knees, and a total fibrous ankylosis that required a knee arthrodesis in one patient. It was concluded from our study that chronic recurrent hemarthrosis and the pain associated with persistent synovitis in the hemophilic knee can be effectively eliminated for as many as twelve years after open synovectomy, although usually with significant loss of motion of the knee. This procedure also appeared to slow the progression of arthropathy, and no patient had been considered for a total knee replacement at the time of writing.
对13例血友病性关节病患者的膝关节进行了滑膜切除术以控制复发性关节积血。术前,所有患者平均每月在患关节发生3次出血事件,并且对至少6个月的药物治疗无反应。影像学检查显示,所有膝关节均为II期或III期血友病性关节病。滑膜切除术时患者的平均年龄为16岁,平均随访时间为7.3年(范围为2至11年7个月)。虽然2例患者术后膝关节活动度未变,但10例患者平均丧失41度。1例患者最终需要关节固定术。影像学检查显示,滑膜切除术后关节有轻微进一步恶化,且无膝关节进展至超过III期血友病性关节病。在我们的系列研究中,只有1例患者滑膜切除术后的膝关节出现复发性自发性关节积血,尽管另外2例有创伤性出血事件。并发症包括3例术后立即出现关节积血需要手术引流,1例患者出现同种免疫性溶血性贫血,2个膝关节出现髌股粘连,1例患者出现完全纤维性强直需要膝关节固定术。我们的研究得出结论,开放性滑膜切除术后,血友病膝关节的慢性复发性关节积血和与持续性滑膜炎相关的疼痛可在长达12年内得到有效消除,尽管通常会伴有膝关节活动度的显著丧失。该手术似乎也减缓了关节病的进展,在撰写本文时,尚无患者考虑进行全膝关节置换。