Kemec Zeki, Tüzün Cevat, Gürel Ali
Nephrology, Batman District State Hospital, Batman, TUR.
Radiology, Batman District State Hospital, Batman, TUR.
Cureus. 2020 Jun 20;12(6):e8707. doi: 10.7759/cureus.8707.
Leukodystrophies are genetic white matter disorders. In the young, they represent an important cause of progressive neurological disability. Impairment of the bladder function may be part of the clinical picture of leukodystrophies. A neurogenic bladder is a dysfunctional urinary bladder caused by a disease of the central or peripheral nervous system involved in the control of micturition. In our patient, leukodystrophy-induced neurogenic bladder and acute kidney injury were revealed. If untreated, a neurogenic bladder can cause renal failure and urinary incontinence. Patients with a neurogenic bladder should be monitored, and management should aim to preserve renal function and achieve social continence.
脑白质营养不良是遗传性白质疾病。在年轻人中,它们是进行性神经功能障碍的重要原因。膀胱功能受损可能是脑白质营养不良临床表现的一部分。神经源性膀胱是由参与排尿控制的中枢或周围神经系统疾病引起的功能失调性膀胱。在我们的患者中,发现了脑白质营养不良引起的神经源性膀胱和急性肾损伤。如果不进行治疗,神经源性膀胱可导致肾衰竭和尿失禁。神经源性膀胱患者应接受监测,治疗应旨在保护肾功能并实现社会可接受的控尿。