Faculty of Pharmacy, Department of Pharmacognosy, El-Menoufia University, El-Menoufia, Egypt.
Faculty of Pharmacy, Department of Pharmacognosy, Al-Azhar University, Cairo, Egypt.
Nat Prod Res. 2021 Dec;35(24):5571-5580. doi: 10.1080/14786419.2020.1797725. Epub 2020 Jul 23.
is wild plant growing in the desert of Egypt, and it has folkloric medicinal uses. Phytochemical investigation of extracts led to the isolation and identification of seven compounds. Among these compounds are three new simple phenolics: Resacetophenone-6-methyl [], Resorcinol [], Resorcinol-O- β -Glucoside []; phenolic ester; and other four known compounds: Methylparaben [4]; two chromones, Noreugenin [], Eugenin []; and one cyclitol: pinitol []. Compounds [] isolated and identified for the first time from natural origin. In contrast, compounds [] isolated for the first time from the family Fabaceae. The biological investigation was conducted on plant extracts and showed that the methylene chloride extract had a strong efficacy against and good activity against In contrast, the n-butanol extract showed extreme cytotoxic activity against Mammary gland breast cancer (MCF-7), and strong activity against Hepatocellular carcinoma (HEPG-2), and Colorectal carcinoma (HCT-116) cell lines.
是一种生长在埃及沙漠中的野生植物，具有民间药用用途。对提取物的植物化学研究导致了七种化合物的分离和鉴定。这些化合物中有三种新的简单酚类化合物：间苯乙酮-6-甲基 []、间苯二酚 []、间苯二酚-O-β-葡萄糖苷 []；酚酯；以及其他四种已知化合物：对羟基苯甲酸甲酯 [4]；两种色酮，新莪术呋喃酮 []、莪术呋喃酮 []；和一种环己醇：松醇 []。化合物 [] 首次从天然产物中分离鉴定。相比之下，化合物 [] 首次从豆科植物中分离鉴定。对植物提取物进行了生物学研究，结果表明二氯甲烷提取物对 具有很强的疗效，对 具有良好的活性。相比之下，正丁醇提取物对乳腺癌（MCF-7）、肝癌（HEPG-2）和结肠癌（HCT-116）细胞系具有极强的细胞毒性活性和很强的活性。
