移植物抗宿主病表现为肌炎和肌坏死。

Graft-Versus-Host Disease Presenting as a Myositis and Myonecrosis.

机构信息

From the Division of Nuclear Medicine and Molecular Imaging, Department of Radiology and Imaging Sciences, Emory University.

出版信息

Clin Nucl Med. 2020 Nov;45(11):e495-e497. doi: 10.1097/RLU.0000000000003201.

DOI:10.1097/RLU.0000000000003201

PMID:32701802

Abstract

Graft-versus-host disease (GVHD) is a major complication of bone marrow transplantation. Polymyositis with myonecrosis is a rare manifestation of GVHD. Here, we report the case of a 32-year-old man with acute myeloid leukemia who developed GVHD after transplant. He subsequently developed polymyositis, which was diagnosed on PET/CT and confirmed on pathology. Treatment with corticosteroids resulted in the resolution of the symptoms. Abnormal muscular FDG uptake resolved on the follow-up PET/CT.

摘要

移植物抗宿主病（GVHD）是骨髓移植的主要并发症。伴有肌肉坏死的多发性肌炎是 GVHD 的一种罕见表现。在这里，我们报告了一例 32 岁男性急性髓细胞白血病患者，在移植后发生 GVHD。随后他出现了多发性肌炎，在 PET/CT 上诊断，并通过病理学得到证实。皮质类固醇治疗后症状得到缓解。异常的肌肉 FDG 摄取在后续的 PET/CT 上得到了缓解。