Fonio de Gijón T, Deza H, Ochoa de Martínez E, Colombo de Holgado S
Servicio de Anatomía Patológica Sanatorio, ADOS, Tucumán.
Acta Gastroenterol Latinoam. 1988;18(3):203-14.
A case of rectal carcinoid tumor in a 54 year old female patient is reported. An endoscopic resection of an elevated high rectal lesion was done after performed a well established radiologic and endoscopic diagnosis. The tumor was localized in the submucosa of the rectum. Microscopically, neoplastic cells were mainly arranged in nests and trabecular structures within thin fibrous stroma. Mitotic figures and pleomorphism cellular were uncommon. Histochemically the argyrophil stain of Grimelius were positive but the Masson-Fontana silver stain were negative. At the ultrastructural level neurosecretory granules were found in the cytoplasma, varied in shape and size, and 150-400 nm in longest axis.
报告了一例54岁女性直肠类癌肿瘤患者。在进行了完善的放射学和内镜诊断后，对直肠高位隆起性病变进行了内镜切除。肿瘤位于直肠黏膜下层。显微镜下，肿瘤细胞主要呈巢状和小梁状结构排列于薄纤维间质内。核分裂象和细胞多形性不常见。组织化学检查显示，Grimelius嗜银染色阳性，但Masson-Fontana银染色阴性。超微结构水平上，细胞质内可见神经分泌颗粒，其形状和大小各异，最长轴为150 - 400nm。
