Medical Gastroenterology, Rolighedsvej 47, Birkerød, Denmark.
Scand J Pain. 2020 Oct 25;20(4):747-753. doi: 10.1515/sjpain-2019-0164.
Objectives A trend for gender-related differences in pain perception during colonoscopies has previously been observed. No consecutive clinical studies have been conducted to confirm such a relation. We aimed to investigate gender-related differences during the colonoscopy procedure, and the impact of endoscopic equipment and psychological factors on pain management. Methods In a consecutive clinical study, 391 patients referred for colonoscopy reported pain perception on a 0-10 visual analogue scale (VAS) after the procedure. A sub-group of patients (n=38) were given alternate instructions expertly tailored by a psychologist and their VAS scores were compared with those from the main study population. Data from a previous study from the same specialist practice and same source patient population using previous-generation equipment was included for comparison. Results No overall gender-related difference in VAS reports was found. There was no reduction in VAS when alternate instructions were given. Female patients were, however, more likely to benefit from light sedation (p=0.012). When compared with previous-generation endoscopes, the current generation equipment resulted in a VAS drop of 1.9 points for women and 1.6 for men (p<0.009) and washed out a previously observed gender-related difference. Conclusion No overall gender-related differences were found for pain experience during the colonoscopy procedure. Access to up-to-date endoscopic equipment can reduce procedure-related patient discomfort considerably, even at the expert level of a consultant physician. Implications Gastroenterologists should consider utilizing high-end endoscopic equipment to improve pain management and reduce VAS to very acceptable levels.
目的 之前曾观察到结肠镜检查中存在与性别相关的疼痛感知差异趋势。但是,没有进行连续的临床研究来证实这种关系。我们旨在研究结肠镜检查过程中的性别差异,以及内镜设备和心理因素对疼痛管理的影响。
方法 在一项连续的临床研究中,391 名因结肠镜检查而就诊的患者在检查后使用 0-10 视觉模拟评分(VAS)报告疼痛感知。一小部分患者(n=38)接受了心理学家专门定制的交替指导,并将他们的 VAS 评分与主要研究人群进行了比较。还包括了来自同一专科医生实践和相同来源患者群体的先前研究的数据,这些数据使用了前一代设备。
结果 未发现 VAS 报告中存在总体性别相关差异。交替指导并未降低 VAS。然而,女性患者更有可能受益于轻度镇静(p=0.012)。与上一代内镜相比,当前代设备使女性的 VAS 降低了 1.9 分,男性降低了 1.6 分(p<0.009),并消除了先前观察到的性别相关差异。
结论 在结肠镜检查过程中,未发现总体性别相关的疼痛体验差异。获得最新的内镜设备可以大大减轻与程序相关的患者不适,即使是在顾问医生的专家水平。
implication 胃肠病学家应考虑使用高端内镜设备来改善疼痛管理并将 VAS 降低到非常可接受的水平。