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基于羧甲基纤维素的抗感染和创伤修复材料:综述。

Carboxymethyl cellulose-based materials for infection control and wound healing: A review.

机构信息

Department of Chemistry, Osmania University, Hyderabad 500 007, Telangana, India.

Centro de Investigaciòn dePolìmeros Avanzados (CIPA), Edificio de Laboratorios, Avenida Collao 1202, Concepciòn, Chile.

出版信息

Int J Biol Macromol. 2020 Dec 1;164:963-975. doi: 10.1016/j.ijbiomac.2020.07.160. Epub 2020 Jul 21.

Abstract

The development of ideal wound dressing materials with excellent characteristics is currently a major demand in wound therapy. In recent years, carboxymethyl cellulose (CMC)-based wound dressing materials have been of immense attraction due to their noble properties, such as: biocompatibility, biodegradability, tissue resembling, low cost and non-toxic. It is used extensively, in a variety of applications in the biomedical and pharmaceutical fields. The hydrophilic nature of CMC, makes it possible to blend and cross-link with other materials, such as: synthetic polymers, natural polymers and inorganic materials and it enables the preparation of innovative wound dressing biomaterials. Hence, this review, focuses on the intrinsic characteristics of CMC-based wound dressing materials, including hydrogels, films, 3D printing, fibres, gauzes and their recent advancements in chronic wound healing.

摘要

理想的伤口敷料材料具有优异的特性,目前是伤口治疗的主要需求。近年来,由于羧甲基纤维素(CMC)基伤口敷料材料具有良好的特性,如生物相容性、可生物降解性、组织相似性、低成本和无毒等,因此受到了极大的关注。它广泛应用于生物医学和制药领域的各种应用中。CMC 的亲水性使其能够与其他材料(如合成聚合物、天然聚合物和无机材料)混合和交联,并能够制备创新的伤口敷料生物材料。因此,本综述重点介绍了基于 CMC 的伤口敷料材料的固有特性,包括水凝胶、薄膜、3D 打印、纤维、纱布及其在慢性伤口愈合方面的最新进展。

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