Brin V B
Zh Evol Biokhim Fiziol. 1978 Nov-Dec;14(6):538-41.
The activity of renin in the blood plasma of 10-, 18--22-day and 2--3-month puppies is higher than in adult dogs. Blocking beta adrenoreceptors in 18--22-day, 2--3 month and adult animals decreases the activity of renin. Hypotensive effect following beta adrenergic block in 10-day puppies and alfa adrenergic block in puppies of all age groups is accompanied by the increase in renin activity. In early ontogenesis, the leading role in regulation of renin secretion belongs to changes in renal hemodynamics.
10日龄、18 - 22日龄以及2 - 3月龄幼犬血浆中的肾素活性高于成年犬。阻断18 - 22日龄、2 - 3月龄及成年动物的β肾上腺素能受体可降低肾素活性。10日龄幼犬β肾上腺素能阻断以及各年龄组幼犬α肾上腺素能阻断后的降压作用伴随着肾素活性增加。在个体发育早期，肾血流动力学变化在肾素分泌调节中起主导作用。
