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源自废弃纺织品的纤维素微珠用于药物递送

Cellulose Beads Derived from Waste Textiles for Drug Delivery.

作者信息

Zeng Beini, Wang Xungai, Byrne Nolene

机构信息

Institute for Frontier Materials, Geelong Waurn Ponds Campus, Deakin University, Waurn Ponds 3216, Victoria, Australia.

出版信息

Polymers (Basel). 2020 Jul 21;12(7):1621. doi: 10.3390/polym12071621.

Abstract

Cellulose beads were successfully prepared from waste denim using a dissolution-regeneration approach with ionic liquids as the dissolving solvent. Cellulose beads with different morphologies were achieved by altering the dissolving and coagulating solvents. The morphological differences were quantified by N physisorption. The impact of morphology on the cellulose beads' potential application was investigated in the context of drug loading and release. The results show that the fibrous morphology showed a better loading capacity than the globular analogue due to its higher surface area and pore volume.

摘要

以离子液体为溶解溶剂,采用溶解-再生法成功地从废旧牛仔布中制备出纤维素珠。通过改变溶解溶剂和凝固溶剂,获得了具有不同形态的纤维素珠。通过N物理吸附对形态差异进行了量化。在药物负载和释放的背景下,研究了形态对纤维素珠潜在应用的影响。结果表明,由于纤维状形态具有较高的表面积和孔体积,其负载能力优于球状类似物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/febf/7407133/e30a309100ff/polymers-12-01621-g001.jpg

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