Berradi Achraf, Aziz Faissal, Achaby Mounir El, Ouazzani Naaila, Mandi Laila
National Center for Research and Studies on Water and Energy (CNEREE), Cadi Ayyad University, P.O. Box 511, Marrakech 40000, Morocco.
Laboratory of Water, Biodiversity and Climate Change, Faculty of Sciences Semlalia, Cadi Ayyad University, P.O. Box 2390, Marrakech 40000, Morocco.
Polymers (Basel). 2023 Jun 30;15(13):2908. doi: 10.3390/polym15132908.
Polysaccharides have emerged as a promising material for hydrogel preparation due to their biocompatibility, biodegradability, and low cost. This review focuses on polysaccharide-based hydrogels' synthesis, characterization, and applications. The various synthetic methods used to prepare polysaccharide-based hydrogels are discussed. The characterization techniques are also highlighted to evaluate the physical and chemical properties of polysaccharide-based hydrogels. Finally, the applications of SAPs in various fields are discussed, along with their potential benefits and limitations. Due to environmental concerns, this review shows a growing interest in developing bio-sourced hydrogels made from natural materials such as polysaccharides. SAPs have many beneficial properties, including good mechanical and morphological properties, thermal stability, biocompatibility, biodegradability, non-toxicity, abundance, economic viability, and good swelling ability. However, some challenges remain to be overcome, such as limiting the formulation complexity of some SAPs and establishing a general protocol for calculating their water absorption and retention capacity. Furthermore, the development of SAPs requires a multidisciplinary approach and research should focus on improving their synthesis, modification, and characterization as well as exploring their potential applications. Biocompatibility, biodegradation, and the regulatory approval pathway of SAPs should be carefully evaluated to ensure their safety and efficacy.
由于多糖具有生物相容性、生物可降解性和低成本等特性，已成为一种很有前景的水凝胶制备材料。本综述聚焦于基于多糖的水凝胶的合成、表征及应用。文中讨论了用于制备基于多糖的水凝胶的各种合成方法。还着重介绍了用于评估基于多糖的水凝胶物理和化学性质的表征技术。最后，讨论了基于多糖的水凝胶在各个领域的应用及其潜在的优点和局限性。出于对环境问题的关注，本综述表明人们对开发由多糖等天然材料制成的生物源水凝胶的兴趣与日俱增。基于多糖的水凝胶具有许多有益特性，包括良好的机械和形态性能、热稳定性、生物相容性、生物可降解性、无毒、储量丰富、经济可行性以及良好的溶胀能力。然而，仍有一些挑战有待克服，例如限制某些基于多糖的水凝胶的配方复杂性，以及建立计算其吸水和保水能力的通用方案。此外，基于多糖的水凝胶的开发需要多学科方法，研究应侧重于改进其合成、改性和表征，以及探索其潜在应用。应仔细评估基于多糖的水凝胶的生物相容性、生物降解性及其监管审批途径，以确保其安全性和有效性。
