“Bayis Ilh Tus - 有力的呼吸”：一个基于社区的研究项目，旨在估计加拿大偏远和农村第一民族社区慢性阻塞性肺疾病的流行情况：研究方案。

"Bayis Ilh Tus - a strong breath" a community-based research project to estimate the prevalence of chronic obstructive pulmonary disease in remote and rural first nations communities in Canada: research protocol.

机构信息

Rehabilitation Sciences Graduate Program, University of British Columbia, Vancouver, Canada.

Centre for Heart Lung Innovation, University of British Columbia, St. Paul's Hospital, 166-1081 Burrard Street, Vancouver, V6Z 1Y6, Canada.

出版信息

Int J Equity Health. 2020 Jul 24;19(1):123. doi: 10.1186/s12939-020-01240-1.

DOI:10.1186/s12939-020-01240-1

PMID:32709235

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7379798/

Abstract

BACKGROUND

Respiratory health conditions appear to be more common among First Nations people versus non-First Nations people in Canada. However, the prevalence of chronic obstructive pulmonary disease (COPD) and its associated risk factors in First Nations communities are unknown. This project aims to estimate the prevalence of COPD in several First Nations communities in British Columbia, Canada and to characterize respiratory symptoms, COPD risk factors, and healthcare utilization.

METHODS

This project is approved by both the University of British Columbia and Carrier Sekani Family Services Research Ethics Boards. We will randomly sample 220 adults, 30 years and older, from 11 participating First Nations. Each participant will complete pre- and post-bronchodilator spirometry tests and the adapted American Thoracic Society Epidemiological Questionnaire with items about smoking history, respiratory symptoms, co-morbidities, and exposures, in order to identify the presence of COPD and its associated individual, occupational, and community risk factors. Homes will be assessed for air quality measures including particulate matter, carbon monoxide and carbon dioxide, and humidity. Health care utilization will be abstracted from the electronic medical record.

DISCUSSION

This is the first project in Canada to estimate the prevalence of COPD in First Nations communities using a random-sampling approach to recruitment. Additionally, although this study will collect detailed information on smoking history, we will also characterize past and current risk factors beyond cigarette smoking. Finally, our methodology ensures that the benefits to the communities are realized during the study period. Individual results will be shared with individuals and health providers to facilitate care. Air quality results will be sent to each Nation's governing council to facilitate remediation where necessary.

TRIAL REGISTRATION

The study has been retrospectively registered at clinicaltrials.gov ( NCT04105088 ).

摘要

背景

在加拿大，与非原住民相比，原住民的呼吸健康状况似乎更为常见。然而，原住民社区慢性阻塞性肺疾病（COPD）及其相关危险因素的流行情况尚不清楚。本项目旨在估计不列颠哥伦比亚省几个原住民社区的 COPD 患病率，并对呼吸症状、COPD 危险因素和医疗保健利用情况进行特征描述。

方法

本项目已获得不列颠哥伦比亚大学和 Carrier Sekani 家庭服务研究伦理委员会的批准。我们将从 11 个参与的原住民社区中随机抽取 220 名 30 岁及以上的成年人。每位参与者将完成预和后支气管扩张剂肺功能测试以及经过改编的美国胸科学会流行病学问卷，其中包含有关吸烟史、呼吸症状、合并症和暴露的项目，以确定 COPD 及其相关的个体、职业和社区危险因素的存在情况。将对房屋的空气质量进行评估，包括颗粒物、一氧化碳和二氧化碳以及湿度。将从电子病历中提取医疗保健利用情况。

讨论

这是加拿大第一个使用随机抽样方法招募原住民社区来估计 COPD 患病率的项目。此外，尽管本研究将收集详细的吸烟史信息，但我们还将描述吸烟以外的过去和当前危险因素。最后，我们的方法学确保了在研究期间社区能够获得收益。个体结果将与个人和医疗保健提供者共享，以促进护理。空气质量结果将发送给每个民族的治理委员会，以便在必要时进行补救。