Department of Pulmonary Medicine, Lung Center of the Philippines, Philippines.
Respirology. 2011 Oct;16(7):1111-8. doi: 10.1111/j.1440-1843.2011.02027.x.
The aim of this study was to determine the prevalence of and risk factors associated with COPD in a rural setting in the Philippines.
The study was conducted in two municipalities in Nueva Ecija province in the Philippines. Using the Burden of Obstructive Lung Disease (BOLD) protocol and study design, non-hospitalized men or women, aged 40years or older, were recruited by multi-stage random sampling procedures. Participants completed questionnaires on respiratory symptoms and exposure to potential risk factors for COPD, including smoking, occupation and exposure to burning of biomass fuel. Spirometry was performed according to American Thoracic Society criteria.
Of the 1188 individuals selected for recruitment, 722 had acceptable post-bronchodilator spirometry and were classified according to Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage. The overall prevalence of COPD for all stages was 20.8%. The prevalence of COPD at GOLD Stage I or higher was greater in men compared with women (26.5% vs 15.3%), and increased between the ages of 40 to >70years. Logistic regression analysis showed a significant association between all stages of COPD and farming for >40years (odds ratio (OR) 2.48, 95% confidence interval (CI): 1.43-4.30), use of firewood for cooking for >60years (OR 3.48, 95% CI: 1.57-7.71), a smoking history of ≥20 pack-years (OR 2.86; 95% CI: 1.78-4.60), and a history of tuberculosis (OR 6.31, 95% CI: 2.67-15.0).
The prevalence COPD in a rural community in Nueva Ecija, Philippines was 20.8% for GOLD Stage I or higher, and 16.7% for GOLD Stage II or higher. In addition to smoking history, the use of firewood for cooking, working on a farm and a history of tuberculosis were significantly associated with fixed airflow obstruction, as assessed by spirometry.
本研究旨在确定菲律宾农村地区 COPD 的患病率及其相关危险因素。
该研究在菲律宾新埃西哈省的两个市进行。采用阻塞性肺病负担（BOLD）方案和研究设计，通过多阶段随机抽样程序招募 40 岁或以上的非住院男性或女性。参与者完成了有关呼吸道症状和 COPD 潜在危险因素暴露情况的调查问卷，包括吸烟、职业和暴露于燃烧生物质燃料。根据美国胸科学会标准进行了肺量测定。
在被选中进行招募的 1188 人中，有 722 人接受了可接受的支气管扩张剂后肺量测定，并根据全球慢性阻塞性肺病倡议（GOLD）阶段进行了分类。所有阶段 COPD 的总体患病率为 20.8%。与女性相比，男性的 GOLD Ⅰ期或更高阶段 COPD 患病率更高（26.5%对 15.3%），且在 40 岁至>70 岁之间增加。Logistic 回归分析显示，所有阶段的 COPD 与从事农业 40 年以上（比值比[OR]2.48，95%置信区间[CI]：1.43-4.30）、使用薪柴烹饪>60 年（OR3.48，95%CI：1.57-7.71）、吸烟史≥20 包年（OR2.86；95%CI：1.78-4.60）和结核病史（OR6.31，95%CI：2.67-15.0）之间存在显著关联。
在菲律宾新埃西哈省的一个农村社区中，GOLD Ⅰ期或更高阶段 COPD 的患病率为 20.8%，GOLD Ⅱ期或更高阶段 COPD 的患病率为 16.7%。除了吸烟史外，使用薪柴烹饪、务农和结核病史与通过肺量测定评估的固定气流受限显著相关。
