Ostermann Marlies, Bellomo Rinaldo, Burdmann Emmanuel A, Doi Kent, Endre Zoltan H, Goldstein Stuart L, Kane-Gill Sandra L, Liu Kathleen D, Prowle John R, Shaw Andrew D, Srisawat Nattachai, Cheung Michael, Jadoul Michel, Winkelmayer Wolfgang C, Kellum John A
Department of Critical Care, King's College London, Guy's & St. Thomas' Hospital, King's College London, London, UK.
Centre for Integrated Critical Care, The University of Melbourne, Melbourne, Victoria, Australia.
Kidney Int. 2020 Aug;98(2):294-309. doi: 10.1016/j.kint.2020.04.020. Epub 2020 Apr 26.
In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the classification and management of acute kidney injury (AKI). The guideline was derived from evidence available through February 2011. Since then, new evidence has emerged that has important implications for clinical practice in diagnosing and managing AKI. In April of 2019, KDIGO held a controversies conference entitled Acute Kidney Injury with the following goals: determine best practices and areas of uncertainty in treating AKI; review key relevant literature published since the 2012 KDIGO AKI guideline; address ongoing controversial issues; identify new topics or issues to be revisited for the next iteration of the KDIGO AKI guideline; and outline research needed to improve AKI management. Here, we present the findings of this conference and describe key areas that future guidelines may address.
2012年,改善全球肾脏病预后组织(KDIGO)发布了一份关于急性肾损伤(AKI)分类和管理的指南。该指南基于截至2011年2月可得的证据制定。自那时起,出现了新的证据,这些证据对AKI诊断和管理的临床实践具有重要意义。2019年4月,KDIGO召开了一次名为“急性肾损伤”的争议会议,目标如下:确定治疗AKI的最佳实践和不确定性领域;回顾自2012年KDIGO AKI指南发布以来发表的关键相关文献;解决当前存在争议的问题;确定KDIGO AKI指南下一版需要重新审视的新主题或问题;并概述改善AKI管理所需的研究。在此,我们展示本次会议的结果,并描述未来指南可能涉及的关键领域。