Department of Respiratory and Sleep Medicine, Austin Health, Melbourne, VIC, Australia.
Institute for Breathing and Sleep, Melbourne, VIC, Australia.
Respirology. 2020 Oct;25(10):1082-1089. doi: 10.1111/resp.13904. Epub 2020 Jul 26.
The TSANZ develops position statements where insufficient data exist to write formal clinical guidelines. In 2018, the TSANZ addressed the question of potential benefits and health impacts of electronic cigarettes (EC). The working party included groups focused on health impacts, smoking cessation, youth issues and priority populations. The 2018 report on the Public Health Consequences of E-Cigarettes from the United States NASEM was accepted as reflective of evidence to mid-2017. A search for papers subsequently published in peer-reviewed journals was conducted in August 2018. A small number of robust and important papers published until March 2019 were also identified and included. Groups identified studies that extended, modified or contradicted the NASEM report. A total of 3793 papers were identified and reviewed, with summaries and draft position statements developed and presented to TSANZ membership in April 2019. After feedback from members and external reviewers, a collection of position statements was finalized in December 2019. EC have adverse lung effects and harmful effects of long-term use are unknown. EC are unsuitable consumer products for recreational use, part-substitution for smoking or long-term exclusive use by former smokers. Smokers who require support to quit smoking should be directed towards approved medication in conjunction with behavioural support as having the strongest evidence for efficacy and safety. No specific EC product can be recommended as effective and safe for smoking cessation. Smoking cessation claims in relation to EC should be assessed by established regulators.
TSANZ 制定立场声明,当存在的数据不足以编写正式的临床指南时。2018 年,TSANZ 探讨了电子烟(EC)的潜在益处和健康影响问题。工作组包括关注健康影响、戒烟、青少年问题和重点人群的小组。美国国家科学院、工程院和医学院 2018 年关于电子烟对公共健康影响的报告被视为反映了截至 2017 年年中的证据。随后在 2018 年 8 月对同行评审期刊上发表的论文进行了搜索。还确定并纳入了截至 2019 年 3 月发表的少量数量虽少但非常重要的论文。各小组确定了扩展、修改或与 NASEM 报告相矛盾的研究。共确定了 3793 篇论文进行审查,总结和草案立场声明编写并提交给 2019 年 4 月的 TSANZ 成员。在成员和外部评论者提供反馈后,2019 年 12 月最终确定了一系列立场声明。EC 对肺部有不良影响,长期使用的有害影响尚不清楚。EC 不适合作为娱乐用途的消费产品,也不适合作为吸烟者替代吸烟或长期独家使用的产品。需要支持戒烟的吸烟者应转向批准的药物,并结合行为支持,因为这是最有证据支持疗效和安全性的方法。没有特定的 EC 产品可以被推荐为有效的戒烟方法。应通过既定监管机构评估与 EC 相关的戒烟声明。