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纳武利尤单抗单药治疗后口腔黏膜黑色素瘤患者的远隔效应:病例报告。

Abscopal effect of radiation therapy after nivolumab monotherapy in a patient with oral mucosal melanoma: A case report.

机构信息

Department of Dentistry and Oral Surgery, Akita University Graduate School of Medicine, Akita, Japan; 44-2 Hasunuma, Hiroomote, Akita-shi, Akita, Japan.

Department of Dentistry and Oral Surgery, Akita University Graduate School of Medicine, Akita, Japan; 44-2 Hasunuma, Hiroomote, Akita-shi, Akita, Japan.

出版信息

Oral Oncol. 2020 Sep;108:104919. doi: 10.1016/j.oraloncology.2020.104919. Epub 2020 Jul 23.

Abstract

The Abscopal effect is a rare phenomenon whereby tumors outside of the irradiated field regress due to systemic antitumor effects of localized radiotherapy. In patients with oral mucosal melanoma, only one instance of the abscopal effect has been described in the English-language literature [1]. Herein, we describe an instance of the abscopal effect following whole-brain radiation therapy after nivolumab monotherapy in a patient with oral mucosal melanoma.

摘要

远隔效应是一种罕见的现象,即由于局部放疗的全身抗肿瘤作用,照射野外的肿瘤消退。在口腔黏膜黑色素瘤患者中,仅有一例远隔效应在英文文献中描述过[1]。在此,我们描述了一例口腔黏膜黑色素瘤患者在接受纳武单抗单药治疗后行全脑放疗出现远隔效应的病例。

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