Campos J L, Subirana J A
Unidad Quimica Macromolecular del C.S.I.C. Escuela T.S. de Ingenieros Industriales, Barcelona, Spain.
J Biomol Struct Dyn. 1987 Aug;5(1):15-9. doi: 10.1080/07391102.1987.10506371.
We have studied by X-ray diffraction fibers of complexes of poly(dG).poly(dC) with N-alpha-acetyl-L-arginine ethylamide. Although these polynucleotides favour the A form of DNA, in this complex it is never found, thus confirming that arginine prevents the appearance of this form of DNA. At high relative humidity the B form is present. Upon dehydration two new structures appear. One of them is a triple helix, most likely formed by poly(dC+).poly(dG).poly(dC). The other structure found also has features which indicate a multistranded conformation.
我们通过X射线衍射研究了聚（dG）·聚（dC）与N-α-乙酰-L-精氨酸乙酰胺复合物的纤维。尽管这些多核苷酸倾向于形成A型DNA，但在该复合物中从未发现这种形式，从而证实精氨酸可阻止这种DNA形式的出现。在高相对湿度下存在B型。脱水后会出现两种新结构。其中一种是三链螺旋，很可能由聚（dC +）·聚（dG）·聚（dC）形成。发现的另一种结构也具有表明多链构象的特征。
